Vagal schwannomas of the head and neck: A comprehensive review and a novel approach to preserving vocal cord innervation and function.


Journal

Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541

Informations de publication

Date de publication:
07 2019
Historique:
received: 21 12 2018
revised: 25 02 2019
accepted: 18 03 2019
pubmed: 9 4 2019
medline: 18 11 2020
entrez: 9 4 2019
Statut: ppublish

Résumé

Schwannomas, benign tumors arising from neurolemmocytes, are the most common type of peripheral nerve tumors. Extracranial schwannomas are most often found in the parapharyngeal space, commonly involving the vagus nerve to cervical sympathetic trunk. Vagal schwannomas present several unique clinical and therapeutic challenges. A comprehensive literature review was conducted on 197 articles reporting 235 cases of cervical vagal schwannomas. Presenting symptoms, treatment approach, and postoperative outcomes were recorded and analyzed. Vagal schwannomas commonly present as asymptomatic neck masses. When they become symptomatic, surgical resection is the standard of care. Gross total resection is associated with higher postoperative morbidity compared to subtotal resection. Initial reports using intraoperative nerve monitoring have shown improved nerve preservation. Recurrence rates are low. The combination of intermittent nerve mapping with novel continuous vagal nerve monitoring techniques may reduce postoperative morbidity and could represent the future standard of care for vagal schwannoma treatment.

Sections du résumé

BACKGROUND
Schwannomas, benign tumors arising from neurolemmocytes, are the most common type of peripheral nerve tumors. Extracranial schwannomas are most often found in the parapharyngeal space, commonly involving the vagus nerve to cervical sympathetic trunk. Vagal schwannomas present several unique clinical and therapeutic challenges.
METHODS
A comprehensive literature review was conducted on 197 articles reporting 235 cases of cervical vagal schwannomas. Presenting symptoms, treatment approach, and postoperative outcomes were recorded and analyzed.
RESULTS
Vagal schwannomas commonly present as asymptomatic neck masses. When they become symptomatic, surgical resection is the standard of care. Gross total resection is associated with higher postoperative morbidity compared to subtotal resection. Initial reports using intraoperative nerve monitoring have shown improved nerve preservation. Recurrence rates are low.
CONCLUSION
The combination of intermittent nerve mapping with novel continuous vagal nerve monitoring techniques may reduce postoperative morbidity and could represent the future standard of care for vagal schwannoma treatment.

Identifiants

pubmed: 30957342
doi: 10.1002/hed.25758
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2450-2466

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Mykayla L Sandler (ML)

THANC (Thyroid, Head and Neck Cancer) Foundation, New York, New York.

John R Sims (JR)

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.

Catherine Sinclair (C)

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.

Kayvon F Sharif (KF)

THANC (Thyroid, Head and Neck Cancer) Foundation, New York, New York.

Rebecca Ho (R)

THANC (Thyroid, Head and Neck Cancer) Foundation, New York, New York.

Lauren E Yue (LE)

THANC (Thyroid, Head and Neck Cancer) Foundation, New York, New York.

Maria J Téllez (MJ)

Department of Intraoperative Neurophysiology, Mount Sinai West Hospital, New York, New York.

Sedat Ulkatan (S)

Department of Intraoperative Neurophysiology, Mount Sinai West Hospital, New York, New York.

Azita S Khorsandi (AS)

Department of Radiology, New York Eye & Ear Infirmary of Mount Sinai, New York, New York.

Margaret Brandwein-Weber (M)

Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York.

Mark L Urken (ML)

THANC (Thyroid, Head and Neck Cancer) Foundation, New York, New York.
Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH