BK virus: Current understanding of pathogenicity and clinical disease in transplantation.


Journal

Reviews in medical virology
ISSN: 1099-1654
Titre abrégé: Rev Med Virol
Pays: England
ID NLM: 9112448

Informations de publication

Date de publication:
07 2019
Historique:
received: 17 12 2018
revised: 28 02 2019
accepted: 01 03 2019
pubmed: 9 4 2019
medline: 9 4 2020
entrez: 9 4 2019
Statut: ppublish

Résumé

BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that continues to pose a significant challenge to clinicians due to its frequently unpredictable onset, persistence, and the lack of effective antiviral agents or prevention strategies. This review covers our current understanding of epidemiology, viral transmission and disease progression, and treatment and prevention strategies that have been used to manage this disease.

Identifiants

pubmed: 30958614
doi: 10.1002/rmv.2044
doi:

Substances chimiques

Immunosuppressive Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2044

Informations de copyright

© 2019 John Wiley & Sons, Ltd.

Auteurs

Stephanie Chong (S)

Department of Renal Medicine, Royal Free Hospital, University College London, London, UK.

Michelle Antoni (M)

School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, London, UK.

Andrew Macdonald (A)

School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, London, UK.

Matthew Reeves (M)

Institute of Immunity and Transplantation, Royal Free Hospital, University College London, London, UK.

Mark Harber (M)

Department of Renal Medicine, Royal Free Hospital, University College London, London, UK.

Ciara N Magee (CN)

Department of Renal Medicine, Royal Free Hospital, University College London, London, UK.

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Classifications MeSH