Macrovascular Complications of Type 2 Diabetes Mellitus.
Type 2 diabetes mellitus
cerebrovascular disease
coronary heart disease
heart failure
hyperglycaemia
macrovascular complications.
Journal
Current vascular pharmacology
ISSN: 1875-6212
Titre abrégé: Curr Vasc Pharmacol
Pays: United Arab Emirates
ID NLM: 101157208
Informations de publication
Date de publication:
2020
2020
Historique:
received:
11
11
2018
revised:
02
12
2018
accepted:
09
12
2018
pubmed:
10
4
2019
medline:
29
9
2020
entrez:
10
4
2019
Statut:
ppublish
Résumé
Type 2 diabetes mellitus (T2DM) has emerged as a pandemic. It has different complications, both microvascular and macrovascular. The purpose of this review is to summarize the different types of macrovascular complications associated with T2DM. A comprehensive review of the literature was performed to identify clinical studies, which determine the macrovascular complications associated with T2DM. Macrovascular complications of T2DM include coronary heart disease, cardiomyopathy, arrhythmias and sudden death, cerebrovascular disease and peripheral artery disease. Cardiovascular disease is the primary cause of death in diabetic patients. Many clinical studies have shown a connection between T2DM and vascular disease, but almost always other risk factors are present in diabetic patients, such as hypertension, obesity and dyslipidaemia. T2DM causes a variety of macrovascular complications through different pathogenetic pathways that include hyperglycaemia and insulin resistance. The association between T2DM and cardiovascular disease is clear, but we need more clinical studies in order to identify the pure effect of T2DM.
Sections du résumé
BACKGROUND
Type 2 diabetes mellitus (T2DM) has emerged as a pandemic. It has different complications, both microvascular and macrovascular.
OBJECTIVE
The purpose of this review is to summarize the different types of macrovascular complications associated with T2DM.
METHODS
A comprehensive review of the literature was performed to identify clinical studies, which determine the macrovascular complications associated with T2DM.
RESULTS
Macrovascular complications of T2DM include coronary heart disease, cardiomyopathy, arrhythmias and sudden death, cerebrovascular disease and peripheral artery disease. Cardiovascular disease is the primary cause of death in diabetic patients. Many clinical studies have shown a connection between T2DM and vascular disease, but almost always other risk factors are present in diabetic patients, such as hypertension, obesity and dyslipidaemia.
CONCLUSION
T2DM causes a variety of macrovascular complications through different pathogenetic pathways that include hyperglycaemia and insulin resistance. The association between T2DM and cardiovascular disease is clear, but we need more clinical studies in order to identify the pure effect of T2DM.
Identifiants
pubmed: 30961498
pii: CVP-EPUB-97859
doi: 10.2174/1570161117666190405165151
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
110-116Informations de copyright
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