Chronic CD30 signaling in B cells results in lymphomagenesis by driving the expansion of plasmablasts and B1 cells.


Journal

Blood
ISSN: 1528-0020
Titre abrégé: Blood
Pays: United States
ID NLM: 7603509

Informations de publication

Date de publication:
13 06 2019
Historique:
received: 12 10 2018
accepted: 08 03 2019
pubmed: 10 4 2019
medline: 10 1 2020
entrez: 10 4 2019
Statut: ppublish

Résumé

CD30 is expressed on a variety of B-cell lymphomas, such as Hodgkin lymphoma, primary effusion lymphoma, and a diffuse large B-cell lymphoma subgroup. In normal tissues, CD30 is expressed on some activated B and T lymphocytes. However, the physiological function of CD30 signaling and its contribution to the generation of CD30

Identifiants

pubmed: 30962205
pii: S0006-4971(20)42490-5
doi: 10.1182/blood.2018880138
doi:

Substances chimiques

Ki-1 Antigen 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2597-2609

Informations de copyright

© 2019 by The American Society of Hematology.

Auteurs

Stefanie Sperling (S)

Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Munich, Germany.

Petra Fiedler (P)

Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Munich, Germany.

Markus Lechner (M)

Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Munich, Germany.

Anna Pollithy (A)

Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Munich, Germany.

Stefanie Ehrenberg (S)

Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Munich, Germany.

Ana-Iris Schiefer (AI)

Department for Experimental and Laboratory Animal Pathology, Medical University Vienna, Vienna, Austria.

Lukas Kenner (L)

Department for Experimental and Laboratory Animal Pathology, Medical University Vienna, Vienna, Austria.
Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria.
Unit of Pathology of Laboratory Animals, University of Veterinary Medicine Vienna, Vienna, Austria.
CBMed Core Lab2, Medical University of Vienna, Vienna, Austria.

Annette Feuchtinger (A)

Research Unit Analytical Pathology, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Munich, Germany.

Ralf Kühn (R)

Max Delbrück Center for Molecular Medicine, Berlin-Buch, Germany.

Gene Swinerd (G)

Experimental Hematology, TranslaTUM, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany; and.

Marc Schmidt-Supprian (M)

Experimental Hematology, TranslaTUM, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany; and.
German Cancer Research Center, German Cancer Consortium, Heidelberg, Germany.

Lothar J Strobl (LJ)

Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Munich, Germany.

Ursula Zimber-Strobl (U)

Research Unit Gene Vectors, Helmholtz Center Munich, German Research Center for Environmental Health GmbH, Munich, Germany.

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Classifications MeSH