A rare case of a gabapentin-induced cardiomyopathy.


Journal

Journal of clinical pharmacy and therapeutics
ISSN: 1365-2710
Titre abrégé: J Clin Pharm Ther
Pays: England
ID NLM: 8704308

Informations de publication

Date de publication:
Aug 2019
Historique:
received: 23 01 2019
revised: 14 03 2019
accepted: 17 03 2019
pubmed: 11 4 2019
medline: 20 12 2019
entrez: 11 4 2019
Statut: ppublish

Résumé

Gabapentin, a γ-aminobutyric acid derivative, is used for the treatment of partial onset seizures, postherpetic neuralgia, diabetic neuropathy and a host of other neurological disorders. A 44-year-old woman with spinal stenosis was prescribed gabapentin for pain. Two months after initiating therapy, she was diagnosed with a new-onset non-ischaemic cardiomyopathy with an ejection fraction of 36% measured on a transthoracic echocardiogram. A patient with suspected gabapentin-induced cardiomyopathy is reported. However, to date, gabapentin therapy has not been associated with risk of the developing a cardiomyopathy.

Identifiants

pubmed: 30968430
doi: 10.1111/jcpt.12840
doi:

Substances chimiques

gamma-Aminobutyric Acid 56-12-2
Gabapentin 6CW7F3G59X

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

644-646

Informations de copyright

© 2019 John Wiley & Sons Ltd.

Auteurs

Katie B Tellor (KB)

St. Louis College of Pharmacy, St. Louis, Missouri.

Richard Ngo-Lam (R)

St. Louis College of Pharmacy, St. Louis, Missouri.

Dena Badran (D)

St. Louis College of Pharmacy, St. Louis, Missouri.

Anastasia L Armbruster (AL)

St. Louis College of Pharmacy, St. Louis, Missouri.

Martin W Schwarze (MW)

BJC Medical Group Cardiology, St. Louis, Missouri.

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Classifications MeSH