Visualization of clustered protocadherin neuronal self-recognition complexes.

Animals Cadherins / chemistry Cryoelectron Microscopy Crystallography, X-Ray Liposomes / chemistry Mice Models, Molecular Neurons / chemistry Protein Domains Protein Multimerization Protocadherins

Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
05 2019
Historique:
received: 03 07 2018
accepted: 07 03 2019
pubmed: 12 4 2019
medline: 22 1 2020
entrez: 12 4 2019
Statut: ppublish

Résumé

Neurite self-recognition and avoidance are fundamental properties of all nervous systems

Identifiants

DOI: 10.1038/s41586-019-1089-3 PMID: 30971825 PMC: PMC6736547
pubmed: 30971825
doi: 10.1038/s41586-019-1089-3
pii: 10.1038/s41586-019-1089-3
pmc: PMC6736547
mid: NIHMS1023915
doi:

Substances chimiques

Cadherins 0
Liposomes 0
Pcdh1 protein, mouse 0
Protocadherins 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

280-283

Subventions

Organisme : NIGMS NIH HHS
ID : F32 GM128303
Pays : United States
Organisme : NIGMS NIH HHS
ID : P41 GM103310
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH114817
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM087237
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM081871
Pays : United States

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Auteurs

Julia Brasch (J)

Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY, USA.
Simons Electron Microscopy Center, New York Structural Biology Center, The National Resource for Automated Molecular Microscopy, New York, NY, USA.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Kerry M Goodman (KM)

Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY, USA.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Alex J Noble (AJ)

Simons Electron Microscopy Center, New York Structural Biology Center, The National Resource for Automated Molecular Microscopy, New York, NY, USA.

Micah Rapp (M)

Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY, USA.
Simons Electron Microscopy Center, New York Structural Biology Center, The National Resource for Automated Molecular Microscopy, New York, NY, USA.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Seetha Mannepalli (S)

Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY, USA.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Fabiana Bahna (F)

Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY, USA.
Howard Hughes Medical Institute, Columbia University, New York, NY, USA.
Department of Systems Biology, Columbia University, New York, NY, USA.

Venkata P Dandey (VP)

Simons Electron Microscopy Center, New York Structural Biology Center, The National Resource for Automated Molecular Microscopy, New York, NY, USA.

Tristan Bepler (T)

Computational and Systems Biology, MIT, Cambridge, MA, USA.
Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA.

Bonnie Berger (B)

Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA.
Department of Mathematics, MIT, Cambridge, MA, USA.

Tom Maniatis (T)

Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY, USA.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Clinton S Potter (CS)

Simons Electron Microscopy Center, New York Structural Biology Center, The National Resource for Automated Molecular Microscopy, New York, NY, USA.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Bridget Carragher (B)

Simons Electron Microscopy Center, New York Structural Biology Center, The National Resource for Automated Molecular Microscopy, New York, NY, USA.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.

Barry Honig (B)

Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY, USA. bh6@cumc.columbia.edu.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA. bh6@cumc.columbia.edu.
Howard Hughes Medical Institute, Columbia University, New York, NY, USA. bh6@cumc.columbia.edu.
Department of Systems Biology, Columbia University, New York, NY, USA. bh6@cumc.columbia.edu.
Department of Medicine, Columbia University, New York, NY, USA. bh6@cumc.columbia.edu.

Lawrence Shapiro (L)

Zuckerman Mind, Brain and Behavior Institute, Columbia University, New York, NY, USA. lss8@columbia.edu.
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA. lss8@columbia.edu.
Department of Systems Biology, Columbia University, New York, NY, USA. lss8@columbia.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Visualization of clustered protocadherin...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Cadhérines › Visualization of clustered protocadherin...
questionsmedicales.fr › Techniques d'investigation › Microscopie électronique › Cryomicroscopie électronique › Visualization of clustered protocadherin...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › Visualization of clustered protocadherin...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomimétiques › Membrane artificielle › Liposomes › Visualization of clustered protocadherin...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Visualization of clustered protocadherin...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles moléculaires › Visualization of clustered protocadherin...
questionsmedicales.fr › Cellules › Neurones › Visualization of clustered protocadherin...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Structure tertiaire des protéines › Domaines protéiques › Visualization of clustered protocadherin...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Multimérisation de protéines › Visualization of clustered protocadherin...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Antigènes de surface › Molécules d'adhérence cellulaire › Cadhérines › Protocadhérines › Visualization of clustered protocadherin...