Mechanical contraction to guide CRT left-ventricular lead placement instead of electrical activation in myocardial infarction with left ventricular dysfunction: An experimental study based on non-invasive gated myocardial perfusion imaging and invasive electroanatomic mapping.


Journal

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
ISSN: 1532-6551
Titre abrégé: J Nucl Cardiol
Pays: United States
ID NLM: 9423534

Informations de publication

Date de publication:
04 2020
Historique:
received: 02 03 2019
accepted: 29 03 2019
pubmed: 12 4 2019
medline: 10 8 2021
entrez: 12 4 2019
Statut: ppublish

Résumé

Whether the region of the latest electrical activation (LEA) corresponds with the segment of the latest mechanical contraction (LMC) in ischemic cardiomyopathy (ICM) is uncertain. We aimed to investigate the relationship between the left-ventricular (LV) viable segments with LEA and with LMC after myocardial infarction (MI) and analyze the acute hemodynamic responses (dP/dt Bama suckling pigs (n = 6) were subjected to create MI models. Both gated myocardial perfusion imaging (GMPI) and electroanatomic mapping (EAM) were performed successfully before MI and 4 weeks after MI. LMC was assessed by phase analysis of GMPI, while LEA was evaluated by EAM. The dP/dt Non-invasive GMPI may be a better option than invasive EAM for guiding LV electrode implantation for CRT in ICM.

Sections du résumé

BACKGROUND
Whether the region of the latest electrical activation (LEA) corresponds with the segment of the latest mechanical contraction (LMC) in ischemic cardiomyopathy (ICM) is uncertain. We aimed to investigate the relationship between the left-ventricular (LV) viable segments with LEA and with LMC after myocardial infarction (MI) and analyze the acute hemodynamic responses (dP/dt
METHODS AND RESULTS
Bama suckling pigs (n = 6) were subjected to create MI models. Both gated myocardial perfusion imaging (GMPI) and electroanatomic mapping (EAM) were performed successfully before MI and 4 weeks after MI. LMC was assessed by phase analysis of GMPI, while LEA was evaluated by EAM. The dP/dt
CONCLUSIONS
Non-invasive GMPI may be a better option than invasive EAM for guiding LV electrode implantation for CRT in ICM.

Identifiants

pubmed: 30972718
doi: 10.1007/s12350-019-01710-2
pii: 10.1007/s12350-019-01710-2
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

419-430

Commentaires et corrections

Type : CommentIn

Références

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Auteurs

Jianfeng Wang (J)

Department of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Yuetao Wang (Y)

Department of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China. yuetao-w@163.com.

Minfu Yang (M)

Department of Nuclear Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100000, China.

Shan Shao (S)

Department of Cardiology, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Yi Tian (Y)

Department of Nuclear Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, China.

Xiaoliang Shao (X)

Department of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Shengdeng Fan (S)

Department of Anesthesiology, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Feifei Zhang (F)

Department of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Wei Yang (W)

Department of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Wenchong Xin (W)

Department of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Haipeng Tang (H)

School of Computing, University of Southern Mississippi, Long Beach, MS, 39560, USA.

Min Xu (M)

Department of Echocardiogram, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Ling Yang (L)

Department of Cardiology, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Xiaosong Wang (X)

Department of Nuclear Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, China.

Weihua Zhou (W)

School of Computing, University of Southern Mississippi, Long Beach, MS, 39560, USA.

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