"Fortunate are those who take the first steps"? The psychosocial impact of novel drug development.

Clinical Trials as Topic Cystic Fibrosis / drug therapy Drug Development Humans Patient Participation / psychology
Clinical research Clinical trials Drug development Psychosocial impact

Journal

Paediatric respiratory reviews
ISSN: 1526-0550
Titre abrégé: Paediatr Respir Rev
Pays: England
ID NLM: 100898941

Informations de publication

Date de publication:
Aug 2019
Historique:
received: 20 02 2019
accepted: 20 02 2019
pubmed: 13 4 2019
medline: 27 2 2020
entrez: 13 4 2019
Statut: ppublish

Résumé

Novel drug development offers people with cystic fibrosis exciting opportunities but is not without challenges. Currently, there is an understandable emphasis on protecting patients' physical health when developing treatments. However, there appears to be little consideration of how novel drug development impacts on psychosocial wellbeing, or the downstream consequences of this. Using an illustrative case and reviewing the literature we explore themes regarding the psychosocial impact of trial participation and novel drug development and identify areas requiring further research. Through this, we hope to prepare healthcare professionals to better understand the needs of their patients in this rapidly evolving landscape.

Identifiants

DOI: 10.1016/j.prrv.2019.02.005 PMID: 30975518
pubmed: 30975518
pii: S1526-0542(19)30019-3
doi: 10.1016/j.prrv.2019.02.005
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

9-11

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Rebecca Dobra (R)

Department of Cystic Fibrosis, Royal Brompton Hospital, London, UK; Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK; National Heart and Lung Institute, Imperial College, London, UK. Electronic address: r.dobra@rbht.nhs.uk.

Susan Madge (S)

Department of Cystic Fibrosis, Royal Brompton Hospital, London, UK.

Isaac Martin (I)

National Heart and Lung Institute, Imperial College, London, UK.

Paul Weldon (P)

Department of Psychological Medicine, Royal Brompton Hospital, London, UK.

Nicholas Simmonds (N)

Department of Cystic Fibrosis, Royal Brompton Hospital, London, UK; National Heart and Lung Institute, Imperial College, London, UK.

Jane C Davies (JC)

Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK; National Heart and Lung Institute, Imperial College, London, UK.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › "Fortunate are those who take the first...
questionsmedicales.fr › Malformations et maladies congénitales, héréditaires et néonatales › Maladies néonatales › Mucoviscidose › "Fortunate are those who take the first...
questionsmedicales.fr › Techniques d'investigation › Développement de médicament › "Fortunate are those who take the first...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › "Fortunate are those who take the first...
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Prestations des soins de santé › Attitude envers la santé › Adhésion et observance thérapeutiques › Acceptation des soins par les patients › Participation des patients › "Fortunate are those who take the first...