Facile

Chemistry Techniques, Synthetic / instrumentation Equipment Design Fluorine Radioisotopes / chemistry Hydrocarbons, Aromatic / chemistry Iodine / chemistry Positron-Emission Tomography Radiopharmaceuticals / chemical synthesis Receptor, Metabotropic Glutamate 5 / metabolism

Journal

Nature protocols
ISSN: 1750-2799
Titre abrégé: Nat Protoc
Pays: England
ID NLM: 101284307

Informations de publication

Date de publication:
05 2019
Historique:
received: 13 06 2017
accepted: 12 02 2019
pubmed: 14 4 2019
medline: 21 5 2019
entrez: 14 4 2019
Statut: ppublish

Résumé

Non-activated (electron-rich and/or sterically hindered) arenes are prevalent chemical scaffolds in pharmaceuticals and positron emission tomography (PET) diagnostics. Despite substantial efforts to develop a general method to introduce

Identifiants

DOI: 10.1038/s41596-019-0149-3 PMID: 30980032
pubmed: 30980032
doi: 10.1038/s41596-019-0149-3
pii: 10.1038/s41596-019-0149-3
doi:

Substances chimiques

Fluorine Radioisotopes 0
Hydrocarbons, Aromatic 0
Radiopharmaceuticals 0
Receptor, Metabotropic Glutamate 5 0
Iodine 9679TC07X4

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1530-1545

Auteurs

Steven H Liang (SH)

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA. liang.steven@mgh.harvard.edu.
ORCID: 0000-0003-1413-6315

Lu Wang (L)

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
ORCID: 0000-0002-8049-1991

Nickeisha A Stephenson (NA)

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
ORCID: 0000-0003-4227-5371

Benjamin H Rotstein (BH)

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
ORCID: 0000-0001-9707-9357

Neil Vasdev (N)

Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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Classifications MeSH

questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Technologie pharmaceutique › Techniques de chimie synthétique › Facile
questionsmedicales.fr › Techniques d'investigation › Conception d'appareillage › Facile
questionsmedicales.fr › Produits chimiques inorganiques › Isotopes › Radio-isotopes › Radio-isotopes du fluor › Facile
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Facile
questionsmedicales.fr › Produits chimiques inorganiques › Éléments › Halogènes › Iode › Facile
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic radioisotopique › Scintigraphie › Tomoscintigraphie › Tomographie par émission de positons › Facile
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Radiopharmaceutiques › Facile
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs aux acides aminés › Récepteurs au glutamate › Récepteurs métabotropes au glutamate › Récepteur-5 métabotropique du glutamate › Facile