Operative vaginal delivery and post-partum infection.


Journal

Best practice & research. Clinical obstetrics & gynaecology
ISSN: 1532-1932
Titre abrégé: Best Pract Res Clin Obstet Gynaecol
Pays: Netherlands
ID NLM: 101121582

Informations de publication

Date de publication:
Apr 2019
Historique:
received: 14 06 2018
revised: 17 09 2018
accepted: 23 09 2018
entrez: 18 4 2019
pubmed: 18 4 2019
medline: 8 8 2019
Statut: ppublish

Résumé

During the past decade, there has been an increase in the awareness of infections associated with pregnancy and delivery. The most significant cause of post-partum infection is caesarean section; 20-25% of operations are followed by wound infections, endometritis or urinary tract infections. Approximately 13% of women in the UK undergo operative vaginal delivery (OVD) with forceps or vacuum, which is also associated with an increased risk of infection, estimated at 0.7%-16% of these deliveries. Despite this, previous reviews have identified only one small trial of antibiotic prophylaxis in 393 women and concluded that there was insufficient evidence to support the routine use of prophylactic antibiotics after OVD. The ANODE trial, a multicentre, blinded, placebo-controlled trial from the UK, is due to report findings from more than 3400 women in 2019 and will be the largest study to date of antibiotic prophylaxis following OVD.

Identifiants

pubmed: 30992125
pii: S1521-6934(18)30212-8
doi: 10.1016/j.bpobgyn.2018.09.005
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

93-106

Subventions

Organisme : Department of Health
ID : HTA/13/96/07
Pays : United Kingdom

Informations de copyright

Copyright © 2018. Published by Elsevier Ltd.

Auteurs

Olaa Mohamed-Ahmed (O)

National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, UK.

Kim Hinshaw (K)

City Hospitals Sunderland NHS Foundation Trust, Faculty of Health Sciences, University of Sunderland, UK.

Marian Knight (M)

National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, UK. Electronic address: marian.knight@npeu.ox.ac.uk.

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