Minimal clinically important differences in Toronto Extremity Salvage Score for patients with lower extremity sarcoma.
Adolescent
Adult
Aged
Aged, 80 and over
Amputation, Surgical
/ methods
Bone Neoplasms
/ surgery
Female
Humans
Limb Salvage
Lower Extremity
/ pathology
Male
Middle Aged
Minimal Clinically Important Difference
Patient Reported Outcome Measures
Sarcoma
/ surgery
Soft Tissue Neoplasms
/ surgery
Young Adult
Journal
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
ISSN: 1436-2023
Titre abrégé: J Orthop Sci
Pays: Japan
ID NLM: 9604934
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
21
12
2018
revised:
05
03
2019
accepted:
22
03
2019
pubmed:
20
4
2019
medline:
24
9
2020
entrez:
20
4
2019
Statut:
ppublish
Résumé
The Toronto Extremity Salvage Score (TESS) is the most widely used patient-reported outcome measure for orthopaedic oncology patients. However, minimal clinically important differences (MCIDs) in the TESS have not been analyzed. The aim of this study was to define the MCIDs of TESS in patients with lower extremity sarcoma. A total of 85 patients were investigated to calculate the MCIDs for TESS. Three different methods were used: 1) distribution-based methods based on one-half of the standard deviation and standard error of measurement (SEM) at the baseline, 2) anchor-based and receiver operating characteristic (ROC) analysis, and 3) anchor-based using Akaike's Information Criterion (AIC) analysis. The MCIDs at 6 months were 4.9-7.8 by distribution-based methods and 4.3-4.4 by anchor-based methods. The MCIDs at 12 months were 4.0-6.9 by distribution-based methods and 10.6-11.6 by anchor-based methods. We calculated MCID values for the TESS based on distribution- and anchor-based approaches. Our results seem reasonable since MCIDs calculated by the different approaches had similar values. This knowledge will enable clinicians to identify meaningful functional improvements in sarcoma patients.
Sections du résumé
BACKGROUND
BACKGROUND
The Toronto Extremity Salvage Score (TESS) is the most widely used patient-reported outcome measure for orthopaedic oncology patients. However, minimal clinically important differences (MCIDs) in the TESS have not been analyzed. The aim of this study was to define the MCIDs of TESS in patients with lower extremity sarcoma.
METHODS
METHODS
A total of 85 patients were investigated to calculate the MCIDs for TESS. Three different methods were used: 1) distribution-based methods based on one-half of the standard deviation and standard error of measurement (SEM) at the baseline, 2) anchor-based and receiver operating characteristic (ROC) analysis, and 3) anchor-based using Akaike's Information Criterion (AIC) analysis.
RESULTS
RESULTS
The MCIDs at 6 months were 4.9-7.8 by distribution-based methods and 4.3-4.4 by anchor-based methods. The MCIDs at 12 months were 4.0-6.9 by distribution-based methods and 10.6-11.6 by anchor-based methods.
CONCLUSIONS
CONCLUSIONS
We calculated MCID values for the TESS based on distribution- and anchor-based approaches. Our results seem reasonable since MCIDs calculated by the different approaches had similar values. This knowledge will enable clinicians to identify meaningful functional improvements in sarcoma patients.
Identifiants
pubmed: 31000377
pii: S0949-2658(19)30118-6
doi: 10.1016/j.jos.2019.03.022
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
315-318Informations de copyright
Copyright © 2019. Published by Elsevier B.V.