Impact of body mass index on post-thyroidectomy morbidity.


Journal

Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541

Informations de publication

Date de publication:
09 2019
Historique:
received: 07 11 2018
revised: 27 03 2019
accepted: 02 04 2019
pubmed: 20 4 2019
medline: 4 11 2020
entrez: 20 4 2019
Statut: ppublish

Résumé

The impact of obesity on total thyroidectomy (TT) morbidity (recurrent laryngeal nerve palsy and hypocalcaemia) remains largely unknown. In a prospective study (NCT01551914), patients were divided into five groups according to their body mass index (BMI): underweight, normal weight, overweight, obese, and severely obese. Preoperative and postoperative serum calcium was measured. Recurrent laryngeal nerve (RLN) function was evaluated before discharge, and if abnormal, at 6 months. In total 1310 patients were included. Baseline characteristics were similar across BMI groups except for age and sex. Postoperative hypocalcaemia was more frequent in underweight compared to obese patients but the difference was not statistically significant in multivariate analysis. There was no difference between groups in terms of definitive hypocalcaemia, transient and definitive RLN palsy, and postoperative pain. Obesity does not increase intraoperative and postoperative morbidity of TT, despite a longer duration of the procedure.

Sections du résumé

BACKGROUND
The impact of obesity on total thyroidectomy (TT) morbidity (recurrent laryngeal nerve palsy and hypocalcaemia) remains largely unknown.
METHODS
In a prospective study (NCT01551914), patients were divided into five groups according to their body mass index (BMI): underweight, normal weight, overweight, obese, and severely obese. Preoperative and postoperative serum calcium was measured. Recurrent laryngeal nerve (RLN) function was evaluated before discharge, and if abnormal, at 6 months.
RESULTS
In total 1310 patients were included. Baseline characteristics were similar across BMI groups except for age and sex. Postoperative hypocalcaemia was more frequent in underweight compared to obese patients but the difference was not statistically significant in multivariate analysis. There was no difference between groups in terms of definitive hypocalcaemia, transient and definitive RLN palsy, and postoperative pain.
CONCLUSION
Obesity does not increase intraoperative and postoperative morbidity of TT, despite a longer duration of the procedure.

Identifiants

pubmed: 31002213
doi: 10.1002/hed.25773
doi:

Substances chimiques

Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2952-2959

Subventions

Organisme : French Ministry of Health
ID : NCT01551914
Pays : International

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Claire Blanchard (C)

CHU de Nantes, Clinique de Chirurgie Digestive et Endocrinienne (CCDE), Nantes Cedex 1, France.

Sahar Bannani (S)

CHU de Nantes, Clinique de Chirurgie Digestive et Endocrinienne (CCDE), Nantes Cedex 1, France.

François Pattou (F)

CHU Lille, Université de Lille, Chirurgie Générale et Endocrinienne, Lille, France.

Laurent Brunaud (L)

CHU Nancy - Hôpital de Brabois, Service de Chirurgie Digestive, Hépato-Biliaire, et Endocrinienne, Nancy, France.

Antoine Hamy (A)

CHU Angers, Chirurgie Digestive et Endocrinienne, Angers Cedex 09, France.

Niki Christou (N)

CHU de Limoges - Hôpital Dupuytren, Chirurgie Digestive, Générale et Endocrinienne, Limoges Cedex, France.

Muriel Mathonnet (M)

CHU de Limoges - Hôpital Dupuytren, Chirurgie Digestive, Générale et Endocrinienne, Limoges Cedex, France.

Marcel Dahan (M)

CHU de Toulouse - Hôpital Larrey, Chirurgie Thoracique, Pôle Voies Respiratoires, Toulouse Cedex 9, France.

Jean-Michel Prades (JM)

CHU Saint-Etienne - Hôpital Nord, ORL et Chirurgie cervico-faciale et plastique, Saint-Etienne Cedex 2, France.

Gérard Landecy (G)

CHU de Besançon - Hôpital Jean Minjoz, Chirurgie digestive, Besançon Cedex, France.

Henri-Pierre Dernis (HP)

Centre Hospitalier du Mans, Service ORL et chirurgie cervico-faciale, Le Mans Cedex 9, France.

Fréderic Sebag (F)

AP-HM - Hôpital de La Timone, Chirurgie Générale, Marseille, France.

Emmanuel Babin (E)

CHU de Caen, ORL et chirurgie cervico-faciale, Caen Cedex 9, France.

Alain Bizon (A)

CHU d'Angers, ORL et chirurgie cervico-faciale, Angers Cedex 09, France.

Jean-Christophe Lifante (JC)

Centre Hospitalier Lyon-Sud, Chirurgie Générale, Endocrinienne, Digestive et Thoracique, Pierre Bénite Cedex, France.

Frank Jegoux (F)

CHU de Rennes - Hôpital Pontchaillou, Service ORL et chirurgie maxillo-faciale, Rennes Cedex 9, France.

Christelle Volteau (C)

CHU de Nantes, DRCI, Département Promotion, Nantes Cedex 1, France.

Cécile Caillard (C)

CHU de Nantes, Clinique de Chirurgie Digestive et Endocrinienne (CCDE), Nantes Cedex 1, France.

Valery-Pierre Riche (VP)

Direction de Recherche clinique, Département Partenariats et Innovation, cellule Innovation, Nantes Cedex 1, France.

Éric Mirallié (É)

CHU de Nantes, Clinique de Chirurgie Digestive et Endocrinienne (CCDE), Nantes Cedex 1, France.

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