[Transbronchial cryobiopsy in diffuse interstitial lung diseases].
Cryobiopsies trans-bronchiques au cours des pneumopathies interstielles diffuses – expériences préliminaires.
Aged
Anesthesia, General
/ adverse effects
Biopsy
/ adverse effects
Bronchoscopy
/ adverse effects
Cryobiology
/ methods
Female
France
/ epidemiology
Humans
Length of Stay
/ statistics & numerical data
Lung
/ pathology
Lung Diseases, Interstitial
/ diagnosis
Male
Middle Aged
Postoperative Complications
/ epidemiology
Predictive Value of Tests
Reproducibility of Results
Retrospective Studies
Sensitivity and Specificity
Biopsie pulmonaire chirurgicale
Bronchoscopie rigide
Cryobiopsies trans-bronchiques
Cryobiopsy
Interstitial lung disease
Interventional pulmonology
Pneumologie interventionnelle
Pneumopathie interstitielle diffuse
Rigid bronchoscopy
Surgical lung biopsy
Journal
Revue des maladies respiratoires
ISSN: 1776-2588
Titre abrégé: Rev Mal Respir
Pays: France
ID NLM: 8408032
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
21
01
2018
accepted:
18
10
2018
pubmed:
22
4
2019
medline:
17
1
2020
entrez:
22
4
2019
Statut:
ppublish
Résumé
In the diagnostic approach to interstitial lung disease (ILD), the use of transbronchial cryobiopsy (TBC) may offer an alternative to surgical lung biopsy (SLB). We report the diagnostic effectiveness and the safety of TBC in ILD based on the preliminary experience in two French university centers. Twenty four patients underwent TBC for the diagnosis of ILD in the operating room between 2014 and 2017. All the histological diagnoses obtained were then reviewed and validated during multidisciplinary discussions (MDD). Patients had an average of 3 TBC.TBC samples were analyzable in 22/24 (91.7%) patients. In these, samples allowed a histological diagnosis to be made in 14/22 (63.6%) patients and a diagnosis with certainty in 13/22 (59%) after MDD. The overall diagnostic yield from TBC was 13/24 (54.2%). Nine (37.5%) patients had a pneumothorax. Five (20.8%) patients had a bleeding. There were no deaths. Taking into account a possible initial learning curve and considering only the 15 patients who had their TBC after 2015, we note that a diagnosis could be made after MDD for 12 of them, that is, 80%. A prospective randomized study is needed to evaluate the technique in France in order to specify its diagnostic performance and its safety profile in comparison to SLB.
Identifiants
pubmed: 31005425
pii: S0761-8425(18)31045-3
doi: 10.1016/j.rmr.2018.10.618
pii:
doi:
Types de publication
Evaluation Study
Journal Article
Multicenter Study
Langues
fre
Sous-ensembles de citation
IM
Pagination
455-460Informations de copyright
Copyright © 2018 SPLF. Published by Elsevier Masson SAS. All rights reserved.