On-the-fly exchangeable microfluidic nozzles for facile production of various monodisperse micromaterials.
Journal
Lab on a chip
ISSN: 1473-0189
Titre abrégé: Lab Chip
Pays: England
ID NLM: 101128948
Informations de publication
Date de publication:
07 06 2019
07 06 2019
Historique:
pubmed:
25
4
2019
medline:
26
12
2019
entrez:
25
4
2019
Statut:
ppublish
Résumé
Microfluidic manufacturing platforms have advanced the production of monodisperse, shape-controlled, and chemically defined micromaterials. However, conventional microfabrication platforms are typically designed and fabricated as single-purpose and single-use tools, which limits their efficiency, versatility, and overall potential. We here present an on-the-fly exchangeable nozzle concept that operates in a transparent, 3D, and reusable microfluidic device produced without cleanroom technology. The facile exchange and repositioning of the nozzles readily enables the production of monodisperse water-in-oil and oil-in-water emulsions, solid and core-shell microspheres, microfibers, and even Janus type micromaterials with controlled diameters ranging from 10 to 1000 μm using a single microfluidic device.
Identifiants
pubmed: 31017163
doi: 10.1039/c9lc00054b
pmc: PMC6555637
mid: NIHMS1025701
doi:
Substances chimiques
Oils
0
Water
059QF0KO0R
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1977-1984Subventions
Organisme : NIAMS NIH HHS
ID : R01 AR074234
Pays : United States
Organisme : NIBIB NIH HHS
ID : R21 EB026824
Pays : United States
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