Do rebreathing manoeuvres for non-invasive measurement of cardiac output during maximum exercise test alter the main cardiopulmonary parameters?


Journal

European journal of preventive cardiology
ISSN: 2047-4881
Titre abrégé: Eur J Prev Cardiol
Pays: England
ID NLM: 101564430

Informations de publication

Date de publication:
10 2019
Historique:
pubmed: 27 4 2019
medline: 22 9 2020
entrez: 27 4 2019
Statut: ppublish

Résumé

Inert gas rebreathing has been recently described as an emergent reliable non-invasive method for cardiac output determination during exercise, allowing a relevant improvement of cardiopulmonary exercise test clinical relevance. For cardiac output measurements by inert gas rebreathing, specific respiratory manoeuvres are needed which might affect pivotal cardiopulmonary exercise test parameters, such as exercise tolerance, oxygen uptake and ventilation vs carbon dioxide output (VE/VCO We retrospectively analysed cardiopulmonary exercise testing of 181 heart failure patients who underwent both cardiopulmonary exercise testing and cardiopulmonary exercise test+cardiac output within two months (average 16 ± 15 days). All patients were in stable clinical conditions (New York Heart Association I-III) and on optimal medical therapy. The majority of patients were in New York Heart Association Class I and II (78.8%), with a mean left ventricular ejection fraction of 31 ± 10%. No difference was found between the two tests in oxygen uptake at peak exercise (1101 (interquartile range 870-1418) ml/min at cardiopulmonary exercise test vs 1103 (844-1389) at cardiopulmonary exercise test-cardiac output) and at anaerobic threshold. However, anaerobic threshold and peak heart rate, peak workload (75 (58-101) watts and 64 (42-90), The similar anaerobic threshold and peak oxygen uptake in the two tests with a lower peak workload and higher VE/VCO

Sections du résumé

BACKGROUND
Inert gas rebreathing has been recently described as an emergent reliable non-invasive method for cardiac output determination during exercise, allowing a relevant improvement of cardiopulmonary exercise test clinical relevance. For cardiac output measurements by inert gas rebreathing, specific respiratory manoeuvres are needed which might affect pivotal cardiopulmonary exercise test parameters, such as exercise tolerance, oxygen uptake and ventilation vs carbon dioxide output (VE/VCO
METHOD
We retrospectively analysed cardiopulmonary exercise testing of 181 heart failure patients who underwent both cardiopulmonary exercise testing and cardiopulmonary exercise test+cardiac output within two months (average 16 ± 15 days). All patients were in stable clinical conditions (New York Heart Association I-III) and on optimal medical therapy.
RESULTS
The majority of patients were in New York Heart Association Class I and II (78.8%), with a mean left ventricular ejection fraction of 31 ± 10%. No difference was found between the two tests in oxygen uptake at peak exercise (1101 (interquartile range 870-1418) ml/min at cardiopulmonary exercise test vs 1103 (844-1389) at cardiopulmonary exercise test-cardiac output) and at anaerobic threshold. However, anaerobic threshold and peak heart rate, peak workload (75 (58-101) watts and 64 (42-90),
CONCLUSION
The similar anaerobic threshold and peak oxygen uptake in the two tests with a lower peak workload and higher VE/VCO

Identifiants

pubmed: 31023097
doi: 10.1177/2047487319845967
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1616-1622

Commentaires et corrections

Type : CommentIn

Auteurs

Carlo Vignati (C)

Centro Cardiologico Monzino, IRCCS, Italy.
Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Italy.

Marco Morosin (M)

Centro Cardiologico Monzino, IRCCS, Italy.
Cardiovascular Department, Azienda Sanitaria-Universitaria Integrata of Trieste, Italy.

Laura Fusini (L)

Centro Cardiologico Monzino, IRCCS, Italy.

Beatrice Pezzuto (B)

Centro Cardiologico Monzino, IRCCS, Italy.

Emanuele Spadafora (E)

Centro Cardiologico Monzino, IRCCS, Italy.

Fabiana De Martino (F)

Centro Cardiologico Monzino, IRCCS, Italy.

Elisabetta Salvioni (E)

Centro Cardiologico Monzino, IRCCS, Italy.

Sara Rovai (S)

Centro Cardiologico Monzino, IRCCS, Italy.
Università degli Studi di Padova, Italy.

Pasquale P Filardi (PP)

Department of Advanced Biomedical Sciences, Federico II University of Naples, Italy.

Gianfranco Sinagra (G)

Cardiovascular Department, Azienda Sanitaria-Universitaria Integrata of Trieste, Italy.

Piergiuseppe Agostoni (P)

Centro Cardiologico Monzino, IRCCS, Italy.
Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Italy.

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