Cholecystostomy: Are we using it correctly?


Journal

American journal of surgery
ISSN: 1879-1883
Titre abrégé: Am J Surg
Pays: United States
ID NLM: 0370473

Informations de publication

Date de publication:
Jun 2019
Historique:
received: 16 03 2018
revised: 02 04 2019
accepted: 04 04 2019
pubmed: 27 4 2019
medline: 14 1 2020
entrez: 27 4 2019
Statut: ppublish

Résumé

Percutaneous Cholecystostomy Tubes (PCT) have become an accepted and common modality of treating acute cholecystitis in patients that are not appropriate surgical candidates. As percutaneous gallbladder drainage has rapidly increased newer research suggests that the technique may be overused, and patients may be burdened with them for extended periods. We examined our experience with PCT placement to identify independent predictors of interval cholecystectomy versus destination PCT. All patients with cholecystitis initially treated with PCT from 2014 to 2017 were stratified by whether they underwent subsequent interval cholecystectomy. Demographic data, initial laboratory values, Tokyo Grade, Charlson Comorbidity Index, ASA Class, complications related to PCT, complications related to cholecystectomy, and mortality data were retrospectively collected. Descriptive statistics, univariable, and multivariable Poisson regression were performed. 165 patients received an initial cholecystostomy tube to treat cholecystitis. 61 (37%) patients went on to have an interval cholecystectomy. There were 4 complications reported after cholecystectomy. A total of 46 (27.9%) deaths were reported, only one of which was in the cholecystectomy group. Age, Tokyo Grade, liver function tests, ASA Class, and Charlson Comorbidity Index were significantly different between the interval cholecystectomy and no-cholecystectomy groups. Univariable regression was performed and variables with p < 0.2 were included in the multivariable model. Multivariable Poisson regression showed that increasing Tokyo Grade (IRR 0.454, p = 0.042, 95% CI 0.194-0.969); and increasing Charlson Comorbidity Score (IRR 0.890, p = 0.026, 95% CI 0.803-0.986) were associated with no-cholecystectomy. Higher Albumin (IRR 1.580, p = 0.011, 95% CI 1.111-2.244) was associated with having an interval cholecystectomy. Patients in the no-cholecystectomy group were older, had more comorbidities, higher Tokyo Grade, ASA Class, and initial liver function test values than those that had interval cholecystectomy. Since interval cholecystectomy was performed with a low rate of complications, we may be too conservative in performing cholecystectomy after drainage and condemning many patients to destination tubes.

Sections du résumé

BACKGROUND BACKGROUND
Percutaneous Cholecystostomy Tubes (PCT) have become an accepted and common modality of treating acute cholecystitis in patients that are not appropriate surgical candidates. As percutaneous gallbladder drainage has rapidly increased newer research suggests that the technique may be overused, and patients may be burdened with them for extended periods. We examined our experience with PCT placement to identify independent predictors of interval cholecystectomy versus destination PCT.
METHODS METHODS
All patients with cholecystitis initially treated with PCT from 2014 to 2017 were stratified by whether they underwent subsequent interval cholecystectomy. Demographic data, initial laboratory values, Tokyo Grade, Charlson Comorbidity Index, ASA Class, complications related to PCT, complications related to cholecystectomy, and mortality data were retrospectively collected. Descriptive statistics, univariable, and multivariable Poisson regression were performed.
RESULTS RESULTS
165 patients received an initial cholecystostomy tube to treat cholecystitis. 61 (37%) patients went on to have an interval cholecystectomy. There were 4 complications reported after cholecystectomy. A total of 46 (27.9%) deaths were reported, only one of which was in the cholecystectomy group. Age, Tokyo Grade, liver function tests, ASA Class, and Charlson Comorbidity Index were significantly different between the interval cholecystectomy and no-cholecystectomy groups. Univariable regression was performed and variables with p < 0.2 were included in the multivariable model. Multivariable Poisson regression showed that increasing Tokyo Grade (IRR 0.454, p = 0.042, 95% CI 0.194-0.969); and increasing Charlson Comorbidity Score (IRR 0.890, p = 0.026, 95% CI 0.803-0.986) were associated with no-cholecystectomy. Higher Albumin (IRR 1.580, p = 0.011, 95% CI 1.111-2.244) was associated with having an interval cholecystectomy.
CONCLUSION CONCLUSIONS
Patients in the no-cholecystectomy group were older, had more comorbidities, higher Tokyo Grade, ASA Class, and initial liver function test values than those that had interval cholecystectomy. Since interval cholecystectomy was performed with a low rate of complications, we may be too conservative in performing cholecystectomy after drainage and condemning many patients to destination tubes.

Identifiants

pubmed: 31023549
pii: S0002-9610(18)30370-2
doi: 10.1016/j.amjsurg.2019.04.002
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1010-1015

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Alexander L Colonna (AL)

University of Utah, Department of Surgery, 30 N 1900 East, Salt Lake City, UT, 84132, USA. Electronic address: Alexander.Colonna@hsc.utah.edu.

Travis M Griffiths (TM)

University of Utah, Department of Surgery, 30 N 1900 East, Salt Lake City, UT, 84132, USA. Electronic address: travis.griffiths@hsc.utah.edu.

Douglas C Robison (DC)

University of Utah, Department of Surgery, 30 N 1900 East, Salt Lake City, UT, 84132, USA. Electronic address: u0736886@utah.edu.

Toby M Enniss (TM)

University of Utah, Department of Surgery, 30 N 1900 East, Salt Lake City, UT, 84132, USA. Electronic address: toby.enniss@hsc.utah.edu.

Jason B Young (JB)

University of Utah, Department of Surgery, 30 N 1900 East, Salt Lake City, UT, 84132, USA. Electronic address: jason.b.young@hsc.utah.edu.

Marta L McCrum (ML)

University of Utah, Department of Surgery, 30 N 1900 East, Salt Lake City, UT, 84132, USA. Electronic address: marta.mccrum@hsc.utah.edu.

Jade M Nunez (JM)

University of Utah, Department of Surgery, 30 N 1900 East, Salt Lake City, UT, 84132, USA. Electronic address: Jade.nunez@hsc.utah.edu.

Raminder Nirula (R)

University of Utah, Department of Surgery, 30 N 1900 East, Salt Lake City, UT, 84132, USA. Electronic address: r.nirula@hsc.utah.edu.

Rulon L Hardman (RL)

University of Utah, Department of Radiology & Imaging Sciences, 30 North 1900 East, Salt Lake City, UT, 84132, USA. Electronic address: rulon.hardman@hsc.utah.edu.

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Classifications MeSH