Targeting Plant ssDNA Viruses with Engineered Miniature CRISPR-Cas14a.

CRISPR-Cas Systems DNA Viruses / genetics Disease Resistance Gene Editing / methods Plant Diseases / prevention & control Plant Viruses / genetics Plants, Genetically Modified / immunology
CRISPR-Cas13a CRISPR-Cas14a CRISPR-Cas9 ssDNA cleavage ssDNA viruses

Journal

Trends in biotechnology
ISSN: 1879-3096
Titre abrégé: Trends Biotechnol
Pays: England
ID NLM: 8310903

Informations de publication

Date de publication:
08 2019
Historique:
received: 23 01 2019
revised: 20 03 2019
accepted: 22 03 2019
pubmed: 27 4 2019
medline: 26 6 2020
entrez: 27 4 2019
Statut: ppublish

Résumé

CRISPR-Cas14a is a highly compact protein with great potential to be used as a guided genome editing tool for single-stranded (ss) DNA cleavage. Recently isolated from noncultured archaea, its unrestricted and sequence-independent cleavage makes it an ideal tool for engineering resistance against economically important plant ssDNA viruses.

Identifiants

DOI: 10.1016/j.tibtech.2019.03.015 PMID: 31023561
pubmed: 31023561
pii: S0167-7799(19)30074-5
doi: 10.1016/j.tibtech.2019.03.015
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

800-804

Informations de copyright

Copyright © 2019. Published by Elsevier Ltd.

Auteurs

Muhammad Zuhaib Khan (MZ)

National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan.

Sibtain Haider (S)

National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan.

Shahid Mansoor (S)

National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan.

Imran Amin (I)

National Institute for Biotechnology and Genetic Engineering (NIBGE), Faisalabad, Pakistan. Electronic address: imranamin1@yahoo.com.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épigenèse génétique › Extinction de l'expression des gènes › Systèmes CRISPR-Cas › Targeting Plant ssDNA Viruses with Engineered...
questionsmedicales.fr › Virus › Virus à ADN › Targeting Plant ssDNA Viruses with Engineered...
questionsmedicales.fr › Phénomènes physiologiques des plantes › Immunité des plantes › Résistance à la maladie › Targeting Plant ssDNA Viruses with Engineered...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Édition de gène › Targeting Plant ssDNA Viruses with Engineered...
questionsmedicales.fr › Phénomènes physiologiques des plantes › Maladies des plantes › Targeting Plant ssDNA Viruses with Engineered...
questionsmedicales.fr › Virus › Virus des plantes › Targeting Plant ssDNA Viruses with Engineered...
questionsmedicales.fr › Stades d'organismes › Organismes génétiquement modifiés › Végétaux génétiquement modifiés › Targeting Plant ssDNA Viruses with Engineered...