Relation of Fontan Baffle Stroke Volume to Fontan Failure and Lower Exercise Capacity in Patients With an Atriopulmonary Fontan.


Journal

The American journal of cardiology
ISSN: 1879-1913
Titre abrégé: Am J Cardiol
Pays: United States
ID NLM: 0207277

Informations de publication

Date de publication:
01 07 2019
Historique:
received: 22 12 2018
revised: 11 03 2019
accepted: 15 03 2019
pubmed: 28 4 2019
medline: 1 2 2020
entrez: 28 4 2019
Statut: ppublish

Résumé

Fontan failure remains a significant problem, especially in patients with an atriopulmonary Fontan. Fontan baffle volume change during the cardiac cycle (Fontan baffle stroke volume) may affect outcomes in Fontan circulation. Assuming that increased Fontan baffle stroke volume is associated with increased energy loss in the baffle, we hypothesized that higher baffle stroke volume is associated with worse exercise capacity and increased incidence of Fontan failure. Patients from 6 centers with an atriopulmonary or lateral tunnel Fontan operation were included if they had a cardiac magnetic resonance (CMR) study and an adequate cardiopulmonary exercise test. Fontan baffle stroke volume was defined as the difference between maximum and minimum Fontan baffle volumes. Fontan failure was defined as death, listing for transplantation, heart failure symptoms requiring medications, or peak VO

Identifiants

pubmed: 31027653
pii: S0002-9149(19)30399-6
doi: 10.1016/j.amjcard.2019.03.040
pii:
doi:

Types de publication

Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

151-157

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Tarek Alsaied (T)

Department of Cardiology, Cincinnati Children's Hospital, Cincinnati, Ohio; Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts. Electronic address: tarek.alsaied@cchmc.org.

Jelle P G van der Ven (JPG)

Department of Pediatrics, Division of Cardiology, Erasmus University Medical Center - Sophia Children's Hospital, Rotterdam, the Netherlands; Netherlands Heart Institute, Utrecht, the Netherlands.

Saeed Juggan (S)

Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

Lynn A Sleeper (LA)

Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

Nina Azcue (N)

Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

Lucia J Kroft (LJ)

Department of Radiology, Leiden University Medical Center, Leiden, the Netherlands.

Andrew J Powell (AJ)

Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

Willem A Helbing (WA)

Department of Pediatrics, Division of Cardiology, Erasmus University Medical Center - Sophia Children's Hospital, Rotterdam, the Netherlands; Department of Pediatrics, Division of Cardiology, Radboud University Medical Center-Amalia Children's Hospital, Nijmegen, the Netherlands; Department of Radiology, Erasmus University Medical Center, Rotterdam, the Netherlands.

Rahul H Rathod (RH)

Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

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