Urban airborne particle exposure impairs human lung and blood
Adult
Bronchoalveolar Lavage Fluid
/ immunology
Cell Survival
/ drug effects
Cytokines
/ biosynthesis
Environmental Exposure
/ adverse effects
Female
Flow Cytometry
/ methods
Host Microbial Interactions
/ immunology
Humans
Inflammation Mediators
/ metabolism
Lung
/ immunology
Male
Mexico
Middle Aged
Mycobacterium tuberculosis
/ immunology
Particle Size
Particulate Matter
/ adverse effects
Phagocytosis
/ drug effects
Urban Health
/ statistics & numerical data
Young Adult
alveolar macrophages
particulate matter
pollution
tuberculosis
Journal
Thorax
ISSN: 1468-3296
Titre abrégé: Thorax
Pays: England
ID NLM: 0417353
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
27
08
2018
revised:
12
02
2019
accepted:
25
02
2019
pubmed:
1
5
2019
medline:
16
5
2020
entrez:
1
5
2019
Statut:
ppublish
Résumé
Associations between urban (outdoor) airborne particulate matter (PM) exposure and TB and potential biological mechanisms are poorly explored. To examine whether in vivo exposure to urban outdoor PM in Mexico City and in vitro exposure to urban outdoor PM Cellular toxicity (flow cytometry, proliferation assay (MTS assay)), In vitro exposure of AM to PM Inhalation exposure to urban air pollution PM impairs important components of the protective human lung and systemic immune response against
Identifiants
pubmed: 31036772
pii: thoraxjnl-2018-212529
doi: 10.1136/thoraxjnl-2018-212529
pmc: PMC7162557
mid: NIHMS1560576
doi:
Substances chimiques
Cytokines
0
Inflammation Mediators
0
Particulate Matter
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
675-683Subventions
Organisme : NIEHS NIH HHS
ID : P30 ES005022
Pays : United States
Organisme : NIEHS NIH HHS
ID : R01 ES020382
Pays : United States
Organisme : NIAMS NIH HHS
ID : U54 AR055073
Pays : United States
Informations de copyright
© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
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