The role of the cerebellum in reconstructing social action sequences: a pilot study.
Aged
Cerebellum
/ physiology
Cognition
Female
Healthy Volunteers
Humans
Magnetic Resonance Imaging
Male
Mentalization
/ physiology
Middle Aged
Neuropsychological Tests
Pilot Projects
Psychomotor Performance
Repression, Psychology
Social Behavior
Social Perception
Spinocerebellar Degenerations
/ physiopathology
Theory of Mind
cerebellum
social mentalizing
theory of mind
Journal
Social cognitive and affective neuroscience
ISSN: 1749-5024
Titre abrégé: Soc Cogn Affect Neurosci
Pays: England
ID NLM: 101288795
Informations de publication
Date de publication:
31 05 2019
31 05 2019
Historique:
received:
04
06
2018
revised:
05
04
2019
accepted:
21
04
2019
pubmed:
1
5
2019
medline:
11
1
2020
entrez:
1
5
2019
Statut:
ppublish
Résumé
Recent research has revealed that the cerebellum plays a critical role in social reasoning and in particular in understanding false beliefs and making trait attributions. One hypothesis is that the cerebellum is responsible for the understanding of sequences of motions and actions, which may be a prerequisite for social understanding. To investigate the role of action sequencing in mentalizing, we tested patients with generalized cerebellar degenerative lesions on tests of social understanding and compared their performance with matched healthy volunteers. The tests involved understanding violations of social norms making trait and causal attributions on the basis of short behavioral sentences and generating the correct chronological order of social actions depicted in cartoons (picture sequencing task). Cerebellar patients showed clear deficits only on the picture sequencing task when generating the correct order of cartoons depicting false belief stories and showed at or close to normal performance for mechanical stories and overlearned social scripts. In addition, they performed marginally worse on trait attributions inferred from verbal behavioral descriptions. We conclude that inferring the mental state of others through understanding the correct sequences of their actions requires the support of the cerebellum.
Identifiants
pubmed: 31037308
pii: 5481626
doi: 10.1093/scan/nsz032
pmc: PMC6545532
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
549-558Informations de copyright
© The Author(s) 2019. Published by Oxford University Press.
Références
Cerebellum. 2016 Dec;15(6):726-731
pubmed: 26563297
Neurology. 2006 Jun 13;66(11):1717-20
pubmed: 16769946
Soc Cogn Affect Neurosci. 2014 Jun;9(6):817-24
pubmed: 23552077
Soc Cogn Affect Neurosci. 2016 Apr;11(4):652-62
pubmed: 26917564
Int J Dev Neurosci. 2005 Apr-May;23(2-3):183-7
pubmed: 15749244
Child Neuropsychol. 2006 Feb;12(1):57-79
pubmed: 16484102
Neurosci Biobehav Rev. 2016 Jun;65:276-91
pubmed: 27073047
Brain. 2000 Jun;123 ( Pt 6):1122-41
pubmed: 10825352
J Autism Dev Disord. 1999 Oct;29(5):407-18
pubmed: 10587887
J Neurophysiol. 2011 Nov;106(5):2322-45
pubmed: 21795627
Neuron. 2014 Aug 6;83(3):518-32
pubmed: 25102558
Front Hum Neurosci. 2014 Jun 25;8:475
pubmed: 25009490
Cerebellum. 2015 Feb;14(1):35-8
pubmed: 25331541
Brain. 2018 Jan 1;141(1):248-270
pubmed: 29206893
Acta Neuropathol. 2017 Jan;133(1):121-138
pubmed: 27704282
J Psychiatr Res. 1975 Nov;12(3):189-98
pubmed: 1202204
Cognition. 1999 May 3;71(1):43-71
pubmed: 10394709
Neuroimage Clin. 2015 Feb 20;7:631-9
pubmed: 25844317
Cerebellum. 2016 Dec;15(6):732-743
pubmed: 26585120
Sci Rep. 2019 Jul 31;9(1):11110
pubmed: 31366954
Nat Rev Neurosci. 2018 Jun;19(6):338-350
pubmed: 29643480
Cogn Affect Behav Neurosci. 2019 Feb;19(1):211-223
pubmed: 30361864
Autism. 2014 Aug;18(6):684-93
pubmed: 24104519
Behav Neurol. 2010;23(1-2):17-29
pubmed: 20714058
Cerebellum. 2012 Mar;11(1):264-71
pubmed: 21842246
Hum Brain Mapp. 2009 Mar;30(3):829-58
pubmed: 18381770
Hum Brain Mapp. 2015 Dec;36(12):5137-54
pubmed: 26419890
Soc Neurosci. 2015 Aug;10(4):337-44
pubmed: 25621820
Behav Res Methods. 2007 May;39(2):175-91
pubmed: 17695343
J Child Psychol Psychiatry. 2001 Feb;42(2):241-51
pubmed: 11280420
J Am Geriatr Soc. 1992 Sep;40(9):922-35
pubmed: 1512391
Neurosci Biobehav Rev. 2014 May;42:9-34
pubmed: 24486722
Neuroimage. 2016 Jan 1;124(Pt A):248-255
pubmed: 26348560
Brain. 2008 May;131(Pt 5):1332-43
pubmed: 18334535
J Neuropsychiatry Clin Neurosci. 2013 Winter;25(1):E48-9
pubmed: 23487232
Neuroimage. 2014 Feb 1;86:554-72
pubmed: 24076206
Nat Rev Neurosci. 2008 Apr;9(4):304-13
pubmed: 18319727
Cerebellum. 2013 Aug;12(4):485-92
pubmed: 23328908
Brain. 2005 May;128(Pt 5):1082-92
pubmed: 15788543