Contribution of Major Polyphenols to the Antioxidant Profile and Cytotoxic Activity of Olive Leaves.
Olea europaea
bioactivities
leaves
phytochemical profile
polyphenols
“Chemlali” cultivar.
Journal
Anti-cancer agents in medicinal chemistry
ISSN: 1875-5992
Titre abrégé: Anticancer Agents Med Chem
Pays: Netherlands
ID NLM: 101265649
Informations de publication
Date de publication:
2019
2019
Historique:
received:
16
01
2019
revised:
28
03
2019
accepted:
29
03
2019
pubmed:
1
5
2019
medline:
9
4
2020
entrez:
1
5
2019
Statut:
ppublish
Résumé
This study was designed to investigate the phytochemical profile and the cytotoxic activities of the eco-friendly extracts of olive leaves from The Phenolic composition of olive leaves extracts, the antioxidant activity and the cytotoxic effects against MCF-7 and HepG2 cells were determined. Olive leaves extracts showed relevant total polyphenols contents. Oleuropein was the major detected phenolic compound reaching a concentration of 16.9 mg/ml. The antioxidant potential of the studied extracts varied from 23.7 to 46.5mM Trolox equivalents as revealed by DPPH and ABTS assays. Cytotoxicity experiments showed similar trends for both HepG2 and MCF-7 cells with the infusion extract being the most active. This study denotes that olive leaves may have great potential as endless bioresource of valuable bioactive compounds which may have a wide application.
Identifiants
pubmed: 31038081
pii: ACAMC-EPUB-98086
doi: 10.2174/1871520619666190416101622
doi:
Substances chimiques
Antineoplastic Agents, Phytogenic
0
Antioxidants
0
Plant Extracts
0
Polyphenols
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1651-1657Informations de copyright
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.