Process design and development of a mammalian cell perfusion culture in shake-tube and benchtop bioreactors.

Animals Bioreactors CHO Cells Cell Count Cell Culture Techniques / instrumentation Cell Survival Cricetulus Equipment Design Perfusion / instrumentation
CHO cells perfusion culture process development scale-down model

Journal

Biotechnology and bioengineering
ISSN: 1097-0290
Titre abrégé: Biotechnol Bioeng
Pays: United States
ID NLM: 7502021

Informations de publication

Date de publication:
08 2019
Historique:
received: 20 12 2018
revised: 15 03 2019
accepted: 18 04 2019
pubmed: 1 5 2019
medline: 5 8 2020
entrez: 1 5 2019
Statut: ppublish

Résumé

The development of mammalian cell perfusion cultures is still laborious and complex to perform due to the limited availability of scale-down models and limited knowledge of time- and cost-effective procedures. The maximum achievable viable cell density (VCD

Identifiants

DOI: 10.1002/bit.26999 PMID: 31038199
pubmed: 31038199
doi: 10.1002/bit.26999
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1973-1985

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Moritz K F Wolf (MKF)

Department of Chemistry and Applied Biosciences, Institute of Chemical and Bioengineering, ETH Zurich, Zurich, Switzerland.

Andrea Müller (A)

Department of Chemistry and Applied Biosciences, Institute of Chemical and Bioengineering, ETH Zurich, Zurich, Switzerland.

Jonathan Souquet (J)

Biotech Process Sciences, Merck Biopharma, Corsier-sur-Vevey, Switzerland.

Hervé Broly (H)

Biotech Process Sciences, Merck Biopharma, Corsier-sur-Vevey, Switzerland.

Massimo Morbidelli (M)

Department of Chemistry and Applied Biosciences, Institute of Chemical and Bioengineering, ETH Zurich, Zurich, Switzerland.
ORCID: 0000-0002-0112-414X

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Process design and development of a mammalian...
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Biotechnologie › Bioréacteurs › Process design and development of a mammalian...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules CHO › Process design and development of a mammalian...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Numération cellulaire › Process design and development of a mammalian...
questionsmedicales.fr › Techniques d'investigation › Techniques in vitro › Techniques de culture › Techniques de culture cellulaire › Process design and development of a mammalian...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › Process design and development of a mammalian...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Arvicolinae › Cricetinae › Cricetulus › Process design and development of a mammalian...
questionsmedicales.fr › Techniques d'investigation › Conception d'appareillage › Process design and development of a mammalian...
questionsmedicales.fr › Techniques d'investigation › Perfusion › Process design and development of a mammalian...