Endogenous CD4
Aged
Antigens, Neoplasm
/ immunology
CD4-Positive T-Lymphocytes
/ immunology
Carcinoma, Non-Small-Cell Lung
/ genetics
Cell Line, Tumor
Computational Biology
/ methods
Female
Gene Expression
Humans
Lung Neoplasms
/ diagnosis
Lymphocyte Activation
Lymphocytes, Tumor-Infiltrating
/ immunology
Male
Middle Aged
Mutation
Neoplasm Staging
Proto-Oncogene Proteins p21(ras)
/ genetics
RNA, Messenger
Receptor, ErbB-2
/ genetics
Transcriptome
Journal
Cancer immunology research
ISSN: 2326-6074
Titre abrégé: Cancer Immunol Res
Pays: United States
ID NLM: 101614637
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
15
06
2018
revised:
12
11
2018
accepted:
24
04
2019
pubmed:
3
5
2019
medline:
6
8
2020
entrez:
3
5
2019
Statut:
ppublish
Résumé
T cells specific for neoantigens encoded by mutated genes in cancers are increasingly recognized as mediators of tumor destruction after immune-checkpoint inhibitor therapy or adoptive cell transfer. Much of the focus has been on identifying epitopes presented to CD8
Identifiants
pubmed: 31043415
pii: 2326-6066.CIR-18-0402
doi: 10.1158/2326-6066.CIR-18-0402
pmc: PMC6584616
mid: NIHMS1528384
doi:
Substances chimiques
Antigens, Neoplasm
0
KRAS protein, human
0
RNA, Messenger
0
ERBB2 protein, human
EC 2.7.10.1
Receptor, ErbB-2
EC 2.7.10.1
Proto-Oncogene Proteins p21(ras)
EC 3.6.5.2
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
910-922Subventions
Organisme : NCI NIH HHS
ID : K12 CA076930
Pays : United States
Organisme : NCI NIH HHS
ID : P50 CA228944
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA114536
Pays : United States
Organisme : NCI NIH HHS
ID : T32 CA009515
Pays : United States
Informations de copyright
©2019 American Association for Cancer Research.
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