Apneas of Heart Failure and Phenotype-Guided Treatments: Part One: OSA.
Acetazolamide
/ therapeutic use
Carbon Dioxide
Carbonic Anhydrase Inhibitors
/ therapeutic use
Continuous Positive Airway Pressure
/ methods
Electric Stimulation Therapy
Exercise
Heart Failure
/ complications
Humans
Hypoglossal Nerve
Muscle Hypotonia
Oxygen Inhalation Therapy
Pharyngeal Muscles
Phenotype
Sleep Apnea, Obstructive
/ complications
Hunter-Cheyne-Stokes breathing
adaptive servo-ventilation
central sleep apnea
heart failure
noninvasive ventilation
oxygen
positive airway pressure
Journal
Chest
ISSN: 1931-3543
Titre abrégé: Chest
Pays: United States
ID NLM: 0231335
Informations de publication
Date de publication:
02 2020
02 2020
Historique:
received:
28
11
2018
revised:
13
02
2019
accepted:
15
02
2019
pubmed:
3
5
2019
medline:
29
7
2020
entrez:
4
5
2019
Statut:
ppublish
Résumé
Sleep-disordered breathing (SDB), including OSA and central sleep apnea, is highly prevalent in patients with heart failure (HF). Multiple studies have reported this high prevalence in asymptomatic as well as symptomatic patients with reduced left ventricular ejection fraction (HFrEF), as well as in those with HF with preserved ejection fraction. The acute pathobiologic consequences of OSA, including exaggerated sympathetic activity, oxidative stress, and inflammation, eventually could lead to progressive left ventricular dysfunction, repeated hospitalization, and excessive mortality. Large numbers of observational studies and a few small randomized controlled trials have shown improvement in various cardiovascular consequences of SDB with treatment. There are no long-term randomized controlled trials to show improved survival of patients with HF and treatment of OSA. One trial of positive airway pressure treatment of OSA included patients with HF and showed no improvement in clinical outcomes. However, any conclusions derived from this trial must take into account several important pitfalls that have been extensively discussed in the literature. With the role of positive airway pressure as the sole therapy for SDB in HF increasingly questioned, a critical examination of long-accepted concepts in this field is needed. The objective of this review was to incorporate recent advances in the field into a phenotype-based approach to the management of OSA in HF.
Identifiants
pubmed: 31047953
pii: S0012-3692(19)30888-8
doi: 10.1016/j.chest.2019.02.407
pmc: PMC7005380
pii:
doi:
Substances chimiques
Carbonic Anhydrase Inhibitors
0
Carbon Dioxide
142M471B3J
Acetazolamide
O3FX965V0I
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
394-402Subventions
Organisme : NHLBI NIH HHS
ID : UG3 HL140144
Pays : United States
Informations de copyright
Copyright © 2019 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.
Références
Eur Heart J. 2016 Jun 1;37(21):1695-703
pubmed: 26612581
J Am Coll Cardiol. 2013 Mar 26;61(12):1259-67
pubmed: 23500328
Thorax. 1988 Feb;43(2):113-9
pubmed: 3127912
Am J Respir Crit Care Med. 2001 May;163(6):1298-301
pubmed: 11371388
Circulation. 1998 Nov 24;98(21):2269-75
pubmed: 9826313
J Appl Physiol (1985). 2013 Apr;114(7):911-22
pubmed: 23349453
J Am Coll Cardiol. 2017 Feb 21;69(7):841-858
pubmed: 28209226
Sleep. 2014 Apr 01;37(4):811-9
pubmed: 24899767
Eur Respir J. 2018 Sep 27;52(3):
pubmed: 30139771
J Card Fail. 2012 Jul;18(7):534-40
pubmed: 22748486
Sleep. 1999 Dec 15;22(8):1101-6
pubmed: 10617171
Eur Respir J. 2016 Nov;48(5):1340-1350
pubmed: 27799387
Circulation. 2013 Oct 15;128(16):1810-52
pubmed: 23741057
Am J Respir Crit Care Med. 2002 Jan 15;165(2):152-8
pubmed: 11790646
J Am Coll Cardiol. 2014 Apr 1;63(12):1123-1133
pubmed: 24491689
Am J Respir Crit Care Med. 2002 May 1;165(9):1251-60
pubmed: 11991874
Circulation. 1995 Mar 15;91(6):1725-31
pubmed: 7882480
Am J Respir Crit Care Med. 2000 Dec;162(6):2194-200
pubmed: 11112137
Crit Care Med. 2002 Nov;30(11):2457-61
pubmed: 12441754
Eur Respir J. 2018 May 10;51(5):
pubmed: 29748245
Respir Physiol Neurobiol. 2008 Jul 31;162(2):144-51
pubmed: 18577470
Am J Respir Crit Care Med. 2013 Oct 15;188(8):996-1004
pubmed: 23721582
N Engl J Med. 2014 Jun 12;370(24):2276-85
pubmed: 24918372
Sleep Med. 2007 Aug;8(5):464-70
pubmed: 17512799
Am J Respir Crit Care Med. 2004 Feb 1;169(3):361-6
pubmed: 14597482
Am Rev Respir Dis. 1992 Apr;145(4 Pt 1):837-40
pubmed: 1554211
Am J Respir Crit Care Med. 2016 Oct 1;194(7):878-885
pubmed: 26967681
Eur Heart J. 2015 Jun 14;36(23):1463-9
pubmed: 25636743
J Appl Physiol (1985). 2008 Sep;105(3):782-90
pubmed: 18583379
Sleep. 2009 May;32(5):637-47
pubmed: 19480231
Lung. 2014 Feb;192(1):175-84
pubmed: 24077936
Heart. 2003 Apr;89(4):404-10
pubmed: 12639868
Am J Respir Crit Care Med. 2006 Jan 15;173(2):234-7
pubmed: 16239622
Int J Cardiol. 2005 Mar 18;99(2):171-85
pubmed: 15749172
Swed Dent J Suppl. 2004;(168):1-56
pubmed: 15638133
J Clin Sleep Med. 2017 Dec 15;13(12):1411-1422
pubmed: 29065958
N Engl J Med. 2014 Jan 9;370(2):139-49
pubmed: 24401051
Am J Respir Crit Care Med. 2001 Sep 1;164(5):807-12
pubmed: 11549537
J Toxicol Environ Health. 1984;14(2-3):137-43
pubmed: 6502730
J Physiol. 2012 Mar 1;590(5):1199-211
pubmed: 22219335
Hypertension. 2005 Dec;46(6):1327-32
pubmed: 16286569
Circ Heart Fail. 2013 May;6(3):606-19
pubmed: 23616602
Sleep. 2009 Oct;32(10):1355-65
pubmed: 19848364
Am J Med. 2003 Jun 1;114(8):625-30
pubmed: 12798449
Am J Respir Crit Care Med. 2009 Feb 1;179(3):241-6
pubmed: 19011149
Circulation. 2001 May 15;103(19):2336-8
pubmed: 11352880
N Engl J Med. 2016 Sep 8;375(10):919-31
pubmed: 27571048
Chest. 2018 Oct;154(4):808-817
pubmed: 30213463
Chest. 2009 Oct;136(4):991-997
pubmed: 19567491
Sleep Breath. 2006 Jun;10(2):90-7
pubmed: 16534592
Br J Clin Pharmacol. 1983;16 Suppl 2:245S-250S
pubmed: 6140945
Respiration. 2001;68(6):566-72
pubmed: 11786710
J Am Coll Cardiol. 2007 Jan 30;49(4):450-8
pubmed: 17258090
Am J Respir Crit Care Med. 2011 Feb 15;183(4):539-46
pubmed: 20656940
Sleep. 2015 Jul 01;38(7):1067-73
pubmed: 25845687
Am J Respir Crit Care Med. 2009 May 15;179(10):962-6
pubmed: 19234106