Changes in apoptosis, proliferation and T lymphocyte subtype on thymic cells of SPF chickens infected with reticuloendotheliosis virus.
Animals
Apoptosis
/ immunology
CD4-Positive T-Lymphocytes
/ immunology
CD8-Positive T-Lymphocytes
/ immunology
Cell Cycle
/ immunology
Cell Proliferation
/ physiology
Chickens
/ immunology
Cyclin D1
/ immunology
Gene Dosage
/ immunology
Genome, Viral
/ immunology
Immunosuppression Therapy
/ methods
Poultry Diseases
/ immunology
Proto-Oncogene Proteins c-bcl-2
/ immunology
Reticuloendotheliosis virus
/ immunology
Retroviridae Infections
/ immunology
T-Lymphocyte Subsets
/ immunology
Thymus Gland
/ immunology
Apoptosis
Immunosuppression
Proliferation
Reticuloendotheliosis
T cell subtype
Virus
Journal
Molecular immunology
ISSN: 1872-9142
Titre abrégé: Mol Immunol
Pays: England
ID NLM: 7905289
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
02
02
2018
revised:
28
01
2019
accepted:
10
04
2019
pubmed:
3
5
2019
medline:
30
10
2019
entrez:
4
5
2019
Statut:
ppublish
Résumé
Reticuloendotheliosis virus (REV), an avian retrovirus is able to infect a variety of birds and can cause immunosuppression. The aim of this study was to investigate the relationship of thymic lymphocytes apoptosis, proliferation and T cell subtype with immunosuppression. In this study, a hundred and twenty one-day old SPF chickens were randomly divided into control groups (group C) and a REV infection groups (group I). The chickens of group I received intraperitoneal injections of REV with 10
Identifiants
pubmed: 31048099
pii: S0161-5890(19)30263-9
doi: 10.1016/j.molimm.2019.04.003
pii:
doi:
Substances chimiques
Proto-Oncogene Proteins c-bcl-2
0
Cyclin D1
136601-57-5
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
87-94Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.