Phenyleneethynylene trimer-based rigid-flexible [2+2] macrocycles for nucleic acid labelling in live cells.

Alkynes / chemistry Ethers / chemistry HeLa Cells Humans Macrocyclic Compounds / chemistry Nucleic Acids / chemistry Polymers / chemistry Proton Magnetic Resonance Spectroscopy

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
21 May 2019
Historique:
pubmed: 3 5 2019
medline: 16 7 2019
entrez: 4 5 2019
Statut: ppublish

Résumé

Fluorescent macromolecules were developed for intracellular labeling in live cells. Coupling rigid rod phenyleneethynylene trimers with flexible amphiphilic diamines via the imine-bond formation chemistry yielded rigid-flexible [2+2] macromolecules showing nucleic acid selectivity and nontoxicity in live cells.

Identifiants

DOI: 10.1039/c9cc02162k PMID: 31049491
pubmed: 31049491
doi: 10.1039/c9cc02162k
doi:

Substances chimiques

Alkynes 0
Ethers 0
Macrocyclic Compounds 0
Nucleic Acids 0
Polymers 0
phenyleneethynylene 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

5930-5933

Auteurs

Joong Ho Moon (JH)

Department of Chemistry and Biochemistry, Biomolecular Sciences Institute, Florida International University, 11200 SW 8th St., Miami, FL 33199, USA. jmoon@fiu.edu.

Prakash Manandhar (P)

Hooman Torabi (H)

Md Rumum Rohman (MR)

Logesh Mathivathanan (L)

Ka Hung Lee (KH)

Stephan Irle (S)

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures acycliques › Alcynes › Phenyleneethynylene trimer-based...
questionsmedicales.fr › Composés chimiques organiques › Éthers › Phenyleneethynylene trimer-based...
questionsmedicales.fr › Cellules › Cellules épithéliales › Cellules HeLa › Phenyleneethynylene trimer-based...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Phenyleneethynylene trimer-based...
questionsmedicales.fr › Composés polycycliques › Composés macrocycliques › Phenyleneethynylene trimer-based...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › Phenyleneethynylene trimer-based...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Phenyleneethynylene trimer-based...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Spectroscopie par résonance magnétique du proton › Phenyleneethynylene trimer-based...