Phenotype of ribonuclease 1 deficiency in mice.

Animals Blood Coagulation Body Size Eosinophil-Derived Neurotoxin / deficiency Factor XI / metabolism Factor XII / metabolism Female Fertility Gene Knockout Techniques Male Mice Models, Animal Phenotype RNA / blood RNA Stability Up-Regulation
blood coagulation eRNA gene knockout mouse ribonuclease

Journal

RNA (New York, N.Y.)
ISSN: 1469-9001
Titre abrégé: RNA
Pays: United States
ID NLM: 9509184

Informations de publication

Date de publication:
08 2019
Historique:
received: 19 01 2019
accepted: 27 04 2019
pubmed: 6 5 2019
medline: 5 11 2019
entrez: 5 5 2019
Statut: ppublish

Résumé

Biological roles for extracellular RNA (eRNA) have become apparent. For example, eRNA can induce contact activation in blood via activation of the plasma proteases factor XII (FXII) and factor XI (FXI). We sought to reveal the biological role of the secretory enzyme ribonuclease 1 (RNase 1) in an organismal context by generating and analyzing RNase 1 knockout (

Identifiants

DOI: 10.1261/rna.070433.119 PMID: 31053653 PMC: PMC6633200
pubmed: 31053653
pii: rna.070433.119
doi: 10.1261/rna.070433.119
pmc: PMC6633200
doi:

Substances chimiques

RNA 63231-63-0
Factor XII 9001-30-3
Factor XI 9013-55-2
Ear2 protein, mouse EC 3.1.-
Eosinophil-Derived Neurotoxin EC 3.1.-

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

921-934

Subventions

Organisme : NCI NIH HHS
ID : R01 CA073808
Pays : United States
Organisme : NHLBI NIH HHS
ID : R35 HL140025
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008688
Pays : United States

Informations de copyright

© 2019 Garnett et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

Références

Eur J Cardiothorac Surg. 2015 Nov;48(5):732-7; discussion 737
pubmed: 25564211
J Biochem. 1986 Jan;99(1):17-25
pubmed: 3514589
Blood. 2008 Oct 15;112(8):3234-41
pubmed: 18647957
Mol Cancer Ther. 2018 Dec;17(12):2622-2632
pubmed: 30282811
Anal Biochem. 1994 May 15;219(1):82-6
pubmed: 7520217
J Mol Biol. 2014 Aug 26;426(17):3041-56
pubmed: 24941155
Blood. 2009 Jul 9;114(2):452-8
pubmed: 19351955
Br J Haematol. 2000 Sep;110(4):946-56
pubmed: 11054087
J Thromb Haemost. 2005 Apr;3(4):695-702
pubmed: 15733058
Blood Rev. 2016 Jan;30(1):11-9
pubmed: 26219246
RNA Biol. 2018 Jan 2;15(1):9-12
pubmed: 29099294
Thromb Haemost. 2004 Sep;92(3):503-8
pubmed: 15351846
Oncotarget. 2016 Dec 27;7(52):87016-87030
pubmed: 27894092
RNA. 2008 Jul;14(7):1424-32
pubmed: 18456845
Blood. 2013 Nov 14;122(20):3415-22
pubmed: 24092932
Semin Thromb Hemost. 2012 Nov;38(8):797-807
pubmed: 23111860
FEBS J. 2014 Dec;281(24):5432-46
pubmed: 25271100
J Thromb Haemost. 2015 Jun;13 Suppl 1:S92-7
pubmed: 26149055
Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6388-93
pubmed: 17405864
Blood. 1997 Nov 15;90(10):3962-6
pubmed: 9354664
J Cell Biochem. 2002;86(3):540-52
pubmed: 12210760
Hippokratia. 2007 Jul;11(3):124-8
pubmed: 19582206
World J Exp Med. 2012 Apr 20;2(2):30-6
pubmed: 24520531
J Thromb Haemost. 2016 Jan;14(1):28-39
pubmed: 26565070
Int J Mol Sci. 2016 Aug 05;17(8):
pubmed: 27527162
Cancer Res. 1977 Mar;37(3):646-50
pubmed: 837366
Blood. 2010 Nov 11;116(19):3981-9
pubmed: 20634381
FEBS Lett. 2010 Jun 3;584(11):2194-200
pubmed: 20388512
Protein Eng. 1995 Mar;8(3):261-73
pubmed: 7479688
Biochemistry. 2011 Sep 20;50(37):7835-41
pubmed: 21838247
Chem Rev. 1998 May 7;98(3):1045-1066
pubmed: 11848924
Blood. 2008 Feb 1;111(3):1274-81
pubmed: 18000168
Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6062-7
pubmed: 15075390
Thromb Res. 2015 Feb;135 Suppl 1:S8-S11
pubmed: 25903541
Thromb Haemost. 2017 Apr 3;117(4):671-681
pubmed: 28124063
Circulation. 2014 Feb 4;129(5):598-606
pubmed: 24201302
J Biol Chem. 2017 Feb 3;292(5):1808-1814
pubmed: 28007958
Nat Protoc. 2008;3(6):1101-8
pubmed: 18546601
Mamm Genome. 2001 May;12(5):352-61
pubmed: 11331942
Endocrinology. 1995 Nov;136(11):5076-83
pubmed: 7588244
Biochem J. 2017 Jun 21;474(13):2219-2233
pubmed: 28495858
Biochemistry. 2019 Feb 19;58(7):987-996
pubmed: 30633504
Genome Res. 2003 Mar;13(3):476-84
pubmed: 12618378
Biopolymers. 2008;90(3):259-77
pubmed: 17868092
Thromb J. 2005 Aug 22;3:12
pubmed: 16115315
Curr Opin Hematol. 2014 Sep;21(5):423-9
pubmed: 25054907
Nucleic Acids Res. 1999 Sep 15;27(18):3696-701
pubmed: 10471739
PLoS One. 2012;7(11):e50399
pubmed: 23226277
Nature. 1969 Jan 25;221(5178):340-4
pubmed: 4974403
Thromb Haemost. 2011 Feb;105(2):345-55
pubmed: 21103661
Anal Biochem. 1984 Jan;136(1):48-64
pubmed: 6201087
Cancer Res. 2013 Aug 15;73(16):5080-9
pubmed: 23774209
Adv Immunol. 2014;121:41-89
pubmed: 24388213
Blood Coagul Fibrinolysis. 1997 Mar;8(2):134-44
pubmed: 9518045
Thromb Res. 2016 May;141 Suppl 2:S4-7
pubmed: 27207422
Blood. 2018 Apr 26;131(17):1903-1909
pubmed: 29483100
Blood Rev. 2014 May;28(3):123-33
pubmed: 24768093
J Biol Chem. 2014 Sep 19;289(38):25996-6006
pubmed: 25078100
Thromb Haemost. 2012 Oct;108(4):730-41
pubmed: 22836360
Front Immunol. 2018 May 16;9:1012
pubmed: 29867984
Nat Methods. 2012 Jul;9(7):671-5
pubmed: 22930834
DNA Cell Biol. 1997 Apr;16(4):413-9
pubmed: 9150428
Cancer Res. 1984 Apr;44(4):1682-7
pubmed: 6704974
Genomics. 2005 Feb;85(2):208-20
pubmed: 15676279
Curr Neurovasc Res. 2009 Feb;6(1):12-9
pubmed: 19355922
Nucleic Acids Res. 2005 Feb 18;33(3):1077-86
pubmed: 15722482
Thromb Haemost. 2006 Jun;95(6):1003-10
pubmed: 16732380

Auteurs

Emily R Garnett (ER)

Graduate Program in Molecular and Cellular Pharmacology, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Jo E Lomax (JE)

Graduate Program Molecular and Cellular and Molecular Biology, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

Bassem M Mohammed (BM)

Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.

David Gailani (D)

Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.
ORCID: 0000-0001-8142-8014

John P Sheehan (JP)

Department of Medicine/Hematology-Oncology, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
ORCID: 0000-0003-1175-760X

Ronald T Raines (RT)

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
ORCID: 0000-0001-7164-1719

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiogiques du sang › Hémostase › Coagulation sanguine › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Mensurations corporelles › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du sang › Immunoprotéines › Protéines des granules de l'éosinophile › Neurotoxine dérivée des éosinophiles › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Facteur XI › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Facteur XII › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Fécondité › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Ciblage de gène › Techniques de knock-out de gènes › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Techniques d'investigation › Modèles animaux › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Stabilité de l'ARN › Phenotype of ribonuclease 1 deficiency in mice.
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Régulation positive › Phenotype of ribonuclease 1 deficiency in mice.