Catechol O-methyltransferase homologs in Schizosaccharomyces pombe are response factors to alkaline and salt stress.
Antacids
/ pharmacology
Catechol O-Methyltransferase
/ genetics
Cloning, Molecular
Gene Expression Regulation, Fungal
Humans
Oligonucleotide Array Sequence Analysis
Promoter Regions, Genetic
Salt Stress
Schizosaccharomyces
/ drug effects
Schizosaccharomyces pombe Proteins
/ genetics
Sequence Homology, Amino Acid
Up-Regulation
Alkaline stress
Catechol O-methyltransferase
Gene expression
Schizosaccharomyces pombe
Journal
Applied microbiology and biotechnology
ISSN: 1432-0614
Titre abrégé: Appl Microbiol Biotechnol
Pays: Germany
ID NLM: 8406612
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
06
03
2019
accepted:
17
04
2019
revised:
28
03
2019
pubmed:
6
5
2019
medline:
13
9
2019
entrez:
5
5
2019
Statut:
ppublish
Résumé
How cells of the fission yeast Schizosaccharomyces pombe respond to alkaline stress is not well understood. Here, to elucidate the molecular mechanism underlying the alkaline stress response in S. pombe, we performed DNA microarray analysis. We found that a homolog of human catechol O-methyltransferase 2 (COMT2) is highly upregulated in S. pombe cells exposed to alkaline conditions. We designated the S. pombe homolog as cmt2
Identifiants
pubmed: 31053915
doi: 10.1007/s00253-019-09858-0
pii: 10.1007/s00253-019-09858-0
doi:
Substances chimiques
Antacids
0
Schizosaccharomyces pombe Proteins
0
Catechol O-Methyltransferase
EC 2.1.1.6
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4881-4887Subventions
Organisme : JSPS KAKENHI
ID : JP17H03966