Application of tRNS to improve multiple sclerosis fatigue: a pilot, single-blind, sham-controlled study.
Fatigue treatment
MFIS
MSQoL-54
Multiple sclerosis
Primary motor area
tRNS
Journal
Journal of neural transmission (Vienna, Austria : 1996)
ISSN: 1435-1463
Titre abrégé: J Neural Transm (Vienna)
Pays: Austria
ID NLM: 9702341
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
received:
14
02
2019
accepted:
22
04
2019
pubmed:
6
5
2019
medline:
28
7
2020
entrez:
5
5
2019
Statut:
ppublish
Résumé
We evaluated the effects of transcranial random noise stimulation (tRNS) on fatigue in 17 subjects with relapsing-remitting multiple sclerosis with low physical disability. Two different patient groups underwent real or sham stimulation for 10 days, targeting the primary motor cortex of the dominant side or contralateral to the most compromised limb. In the 'real group', beneficial effects were observed using the Modified Fatigue Impact Scale (p = 0.04; physical subscale: p = 0.03), the subscales 'change in health' (p = 0.006) and 'role limitations due to physical problems' (p = 0.001) of the Multiple Sclerosis Quality of Life-54, and by assessing the patient impression of perceived fatigue (p = 0.005).
Identifiants
pubmed: 31054015
doi: 10.1007/s00702-019-02006-y
pii: 10.1007/s00702-019-02006-y
doi:
Substances chimiques
Placebos
0
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
795-799Références
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