Tracking Five Millennia of Horse Management with Extensive Ancient Genome Time Series.
ancient DNA
animal breeding
diversity
domestication
equestrian civilizations
extinct lineages
horses
management
mules
selection
Journal
Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066
Informations de publication
Date de publication:
30 05 2019
30 05 2019
Historique:
received:
19
10
2018
revised:
14
02
2019
accepted:
27
03
2019
pubmed:
6
5
2019
medline:
25
3
2020
entrez:
7
5
2019
Statut:
ppublish
Résumé
Horse domestication revolutionized warfare and accelerated travel, trade, and the geographic expansion of languages. Here, we present the largest DNA time series for a non-human organism to date, including genome-scale data from 149 ancient animals and 129 ancient genomes (≥1-fold coverage), 87 of which are new. This extensive dataset allows us to assess the modern legacy of past equestrian civilizations. We find that two extinct horse lineages existed during early domestication, one at the far western (Iberia) and the other at the far eastern range (Siberia) of Eurasia. None of these contributed significantly to modern diversity. We show that the influence of Persian-related horse lineages increased following the Islamic conquests in Europe and Asia. Multiple alleles associated with elite-racing, including at the MSTN "speed gene," only rose in popularity within the last millennium. Finally, the development of modern breeding impacted genetic diversity more dramatically than the previous millennia of human management.
Identifiants
pubmed: 31056281
pii: S0092-8674(19)30384-8
doi: 10.1016/j.cell.2019.03.049
pmc: PMC6547883
pii:
doi:
Substances chimiques
DNA, Ancient
0
Types de publication
Historical Article
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1419-1435.e31Subventions
Organisme : European Research Council
ID : 681605
Pays : International
Organisme : NIMH NIH HHS
ID : U01 MH106874
Pays : United States
Organisme : Austrian Science Fund FWF
ID : W 1225
Pays : Austria
Organisme : Howard Hughes Medical Institute
Pays : United States
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2019 The Author(s). Published by Elsevier Inc. All rights reserved.
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