Assessing the volume of large cerebral arteriovenous malformations: Can the ABC/2 formula reliably predict true volume?


Journal

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
ISSN: 1532-2653
Titre abrégé: J Clin Neurosci
Pays: Scotland
ID NLM: 9433352

Informations de publication

Date de publication:
Jul 2019
Historique:
received: 20 03 2019
accepted: 29 04 2019
pubmed: 9 5 2019
medline: 23 7 2019
entrez: 9 5 2019
Statut: ppublish

Résumé

Outcomes of stereotactic radiosurgery in the treatment of cerebral arteriovenous malformations (AVMs) are volume-dependent. The ability to estimate AVM volume has significant value in guiding AVM management. To determine whether AVM volume measurement calculated from the ABC/2 formula is accurate compared to volume calculated by a computer-assisted planimetric method for large AVMs. Retrospective review of 42 intracranial AVMs >3 cm in diameter that underwent treatment with dose-staged hypofractionated stereotactic radiotherapy (HSRT) from 2001 to 2018. Two raters independently measured pre- and post-HSRT volumes using both the ABC/2 formula and computer-assisted planimetry in a blinded fashion. Inter-rater reliability was assessed by calculation of intra-class correlation coefficient (ICC). Absolute volumes and percent volume change following HSRT as determined using the two methods were compared using paired t-tests, linear regression, and Bland-Altman plot analyses. The ICC between the 2 raters for planimetric and ABC/2 volumes was 0.859 and 0.799, respectively. ABC/2 volumes, 26.1 ± 26.6 cm The ABC/2 and planimetric methods are reproducible for measuring cerebral AVM volumes. Although the ABC/2 method of volume estimation underestimates planimetric AVM volume, the high correlation between the two suggests utility of the ABC/2 method if one understands its limits, particularly with respect to estimating change in AVM volume after treatment.

Sections du résumé

BACKGROUND BACKGROUND
Outcomes of stereotactic radiosurgery in the treatment of cerebral arteriovenous malformations (AVMs) are volume-dependent. The ability to estimate AVM volume has significant value in guiding AVM management.
OBJECTIVE OBJECTIVE
To determine whether AVM volume measurement calculated from the ABC/2 formula is accurate compared to volume calculated by a computer-assisted planimetric method for large AVMs.
METHODS METHODS
Retrospective review of 42 intracranial AVMs >3 cm in diameter that underwent treatment with dose-staged hypofractionated stereotactic radiotherapy (HSRT) from 2001 to 2018. Two raters independently measured pre- and post-HSRT volumes using both the ABC/2 formula and computer-assisted planimetry in a blinded fashion. Inter-rater reliability was assessed by calculation of intra-class correlation coefficient (ICC). Absolute volumes and percent volume change following HSRT as determined using the two methods were compared using paired t-tests, linear regression, and Bland-Altman plot analyses.
RESULTS RESULTS
The ICC between the 2 raters for planimetric and ABC/2 volumes was 0.859 and 0.799, respectively. ABC/2 volumes, 26.1 ± 26.6 cm
CONCLUSION CONCLUSIONS
The ABC/2 and planimetric methods are reproducible for measuring cerebral AVM volumes. Although the ABC/2 method of volume estimation underestimates planimetric AVM volume, the high correlation between the two suggests utility of the ABC/2 method if one understands its limits, particularly with respect to estimating change in AVM volume after treatment.

Identifiants

pubmed: 31064679
pii: S0967-5868(19)30546-6
doi: 10.1016/j.jocn.2019.04.038
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-5

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Alon Kashanian (A)

Department of Neurosurgery, David Geffen School of Medicine at UCLA (University of California, Los Angeles), 300 UCLA Stein Plaza, Suite 420, Los Angeles, CA, USA.

Hiro Sparks (H)

Department of Neurosurgery, David Geffen School of Medicine at UCLA (University of California, Los Angeles), 300 UCLA Stein Plaza, Suite 420, Los Angeles, CA, USA.

Tania Kaprealian (T)

Department of Radiation Oncology, David Geffen School of Medicine at UCLA (University of California, Los Angeles), 200 UCLA Medical Plaza, Suite B265, Los Angeles, CA, USA.

Nader Pouratian (N)

Department of Neurosurgery, David Geffen School of Medicine at UCLA (University of California, Los Angeles), 300 UCLA Stein Plaza, Suite 420, Los Angeles, CA, USA; Department of Radiation Oncology, David Geffen School of Medicine at UCLA (University of California, Los Angeles), 200 UCLA Medical Plaza, Suite B265, Los Angeles, CA, USA. Electronic address: NPouratian@mednet.ucla.edu.

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Classifications MeSH