Investigating the oxygenation of brain arteriovenous malformations using quantitative susceptibility mapping.


Journal

NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515

Informations de publication

Date de publication:
01 10 2019
Historique:
received: 05 03 2019
revised: 23 04 2019
accepted: 06 05 2019
pubmed: 11 5 2019
medline: 28 2 2020
entrez: 11 5 2019
Statut: ppublish

Résumé

Brain arteriovenous malformations (AVMs) are congenital vascular anomalies characterized by arteriovenous shunting through a network of coiled and tortuous vessels. Because of this anatomy, the venous drainage of an AVM is hypothesized to contain more oxygenated, arterialized blood than healthy veins. By exploiting the paramagnetic properties of deoxygenated hemoglobin in venous blood using magnetic resonance imaging (MRI) quantitative susceptibility mapping (QSM), we aimed to explore venous density and oxygen saturation (SvO

Identifiants

pubmed: 31075392
pii: S1053-8119(19)30397-0
doi: 10.1016/j.neuroimage.2019.05.014
pii:
doi:

Substances chimiques

Hemoglobins 0
deoxyhemoglobin 9008-02-0
Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

440-453

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Emma Biondetti (E)

MRI Group, Department of Medical Physics and Biomedical Engineering, Malet Place Engineering Building, University College London, WC1E 6BT, London, UK. Electronic address: emma.biondetti@icm-institute.org.

Alvaro Rojas-Villabona (A)

The Gamma Knife Centre at Queen Square, National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, London, UK; Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, London, UK.

Magdalena Sokolska (M)

Medical Physics and Biomedical Engineering, University College London Hospitals, NW1 2BU, London, UK.

Francesca B Pizzini (FB)

Neuroradiology Unit, Department of Diagnostics and Pathology, Verona University Hospital, Piazzale Stefani, 37126, Verona, Italy.

Hans Rolf Jäger (HR)

The Lysholm Department of Neuroradiology, National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, London, UK; Neuroradiological Academic Unit, UCL Institute of Neurology, University College London, Queen Square, WC1N 3BG, London, UK.

David L Thomas (DL)

Neuroradiological Academic Unit, UCL Institute of Neurology, University College London, Queen Square, WC1N 3BG, London, UK; Leonard Wolfson Experimental Neurology Centre, UCL Institute of Neurology, University College London, Queen Square, WC1N 3BG, London, UK.

Karin Shmueli (K)

MRI Group, Department of Medical Physics and Biomedical Engineering, Malet Place Engineering Building, University College London, WC1E 6BT, London, UK.

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Classifications MeSH