Titre : Globines

Globines : Questions médicales fréquentes

Nom anglais: Globins

Descriptor UI: D005914

Tree Number: D12.776.422.316

Questions fréquentes et termes MeSH associés

Diagnostic 5

#1

Comment diagnostiquer une anomalie des globines ?

Des tests sanguins mesurant les niveaux de globines et des électrophorèses sont utilisés.
Globines Anomalies génétiques
#2

Quels tests sont utilisés pour les troubles des globines ?

Les tests incluent l'électrophorèse des protéines et les tests génétiques.
Électrophorèse Tests génétiques
#3

Quels symptômes indiquent un problème de globines ?

Fatigue, pâleur, essoufflement et anomalies sanguines peuvent indiquer un problème.
Fatigue Anémie
#4

Les globinopathies sont-elles héréditaires ?

Oui, certaines globinopathies comme la drépanocytose sont héréditaires.
Globinopathies Hérédité
#5

Comment évaluer la fonction des globines ?

On évalue la fonction par des tests de saturation en oxygène et des analyses sanguines.
Saturation en oxygène Analyse sanguine

Symptômes 5

#1

Quels sont les symptômes d'une carence en globines ?

Les symptômes incluent fatigue, faiblesse, et essoufflement lors d'efforts.
Fatigue Essoufflement
#2

Comment reconnaître une globinopathie ?

Les signes incluent des douleurs abdominales, des infections fréquentes et une anémie.
Globinopathies Anémie
#3

Les globinopathies causent-elles des douleurs ?

Oui, des douleurs peuvent survenir, surtout en cas de crise vaso-occlusive.
Douleur Crise vaso-occlusive
#4

Quels signes indiquent une surcharge en globines ?

Des signes comme la jaunisse et des douleurs articulaires peuvent apparaître.
Jaunisse Douleurs articulaires
#5

Les symptômes varient-ils selon le type de globinopathie ?

Oui, les symptômes varient selon le type, comme la drépanocytose ou la thalassémie.
Drépanocytose Thalassémie

Prévention 5

#1

Peut-on prévenir les globinopathies ?

La prévention est limitée, mais le dépistage génétique peut aider les familles à risque.
Dépistage génétique Globinopathies
#2

Comment réduire le risque de complications ?

Un suivi médical régulier et un traitement préventif peuvent réduire les risques.
Suivi médical Complications
#3

Le dépistage néonatal est-il utile ?

Oui, le dépistage néonatal permet de détecter précocement les globinopathies.
Dépistage néonatal Globinopathies
#4

Les vaccinations sont-elles importantes pour les patients ?

Oui, les vaccinations aident à prévenir les infections chez les patients à risque.
Vaccinations Infections
#5

Comment l'éducation peut-elle aider à prévenir les globinopathies ?

L'éducation sur les risques et les signes précoces peut aider à une détection rapide.
Éducation Détection précoce

Traitements 5

#1

Quels traitements existent pour les globinopathies ?

Les traitements incluent transfusions sanguines, médicaments et thérapies géniques.
Transfusions sanguines Thérapie génique
#2

La thérapie génique est-elle efficace pour les globinopathies ?

Oui, la thérapie génique montre des résultats prometteurs pour certaines globinopathies.
Thérapie génique Globinopathies
#3

Comment traiter une anémie causée par des globines ?

Le traitement peut inclure des suppléments de fer et des transfusions sanguines.
Anémie Suppléments de fer
#4

Les médicaments peuvent-ils aider les globinopathies ?

Oui, certains médicaments aident à gérer les symptômes et à prévenir les complications.
Médicaments Complications
#5

Quelles sont les options de traitement pour la drépanocytose ?

Les options incluent des transfusions, des médicaments et des traitements préventifs.
Drépanocytose Transfusions sanguines

Complications 5

#1

Quelles complications peuvent survenir avec les globinopathies ?

Les complications incluent des infections, des crises douloureuses et des problèmes organiques.
Infections Complications
#2

Les globinopathies augmentent-elles le risque d'accidents vasculaires ?

Oui, certaines globinopathies augmentent le risque d'accidents vasculaires cérébraux.
Accidents vasculaires cérébraux Globinopathies
#3

Comment gérer les complications des globinopathies ?

La gestion inclut un suivi médical, des traitements symptomatiques et des soins préventifs.
Suivi médical Soins préventifs
#4

Les complications peuvent-elles être évitées ?

Certaines complications peuvent être évitées par un traitement préventif et un suivi régulier.
Traitement préventif Suivi régulier
#5

Les complications affectent-elles la qualité de vie ?

Oui, les complications peuvent significativement affecter la qualité de vie des patients.
Qualité de vie Complications

Facteurs de risque 5

#1

Quels sont les facteurs de risque des globinopathies ?

Les facteurs incluent des antécédents familiaux, l'origine ethnique et certaines conditions médicales.
Antécédents familiaux Origine ethnique
#2

L'origine ethnique influence-t-elle les globinopathies ?

Oui, certaines ethnies, comme les Africains et les Méditerranéens, sont plus à risque.
Origine ethnique Globinopathies
#3

Les femmes enceintes doivent-elles être testées ?

Oui, le dépistage des globinopathies est recommandé pour les femmes enceintes à risque.
Femmes enceintes Dépistage
#4

Les antécédents médicaux augmentent-ils le risque ?

Oui, des antécédents de maladies sanguines augmentent le risque de globinopathies.
Antécédents médicaux Maladies sanguines
#5

Le mode de vie influence-t-il les globinopathies ?

Oui, des facteurs comme la nutrition et l'exercice peuvent influencer la santé des globines.
Mode de vie Nutrition
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"@type": "MedicalCondition", "name": "Globines", "alternateName": "Globins", "code": { "@type": "MedicalCode", "code": "D005914", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Mitchell J Weiss", "url": "https://questionsmedicales.fr/author/Mitchell%20J%20Weiss", "affiliation": { "@type": "Organization", "name": "Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN." } }, { "@type": "Person", "name": "Christophe Lechauve", "url": "https://questionsmedicales.fr/author/Christophe%20Lechauve", "affiliation": { "@type": "Organization", "name": "Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee." } }, { "@type": "Person", "name": "Brant E Isakson", "url": "https://questionsmedicales.fr/author/Brant%20E%20Isakson", "affiliation": { "@type": "Organization", "name": "Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia." } }, { "@type": "Person", "name": "Luc Moens", "url": "https://questionsmedicales.fr/author/Luc%20Moens", "affiliation": { "@type": "Organization", "name": "Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium." } }, { "@type": "Person", "name": "Sylvia Dewilde", "url": "https://questionsmedicales.fr/author/Sylvia%20Dewilde", "affiliation": { "@type": "Organization", "name": "Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Hell's Gate Globin-I from", "datePublished": "2024-06-20", "url": "https://questionsmedicales.fr/article/38928500", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3390/ijms25126794" } }, { "@type": "ScholarlyArticle", "name": "Screening for Antibody Deficiencies in Adults by Serum Electrophoresis and Calculated Globin.", 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et réponses médicales fréquentes sur Globines", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2026-05-12", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Globines", "description": "Comment diagnostiquer une anomalie des globines ?\nQuels tests sont utilisés pour les troubles des globines ?\nQuels symptômes indiquent un problème de globines ?\nLes globinopathies sont-elles héréditaires ?\nComment évaluer la fonction des globines ?", "url": "https://questionsmedicales.fr/mesh/D005914#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Globines", "description": "Quels sont les symptômes d'une carence en globines ?\nComment reconnaître une globinopathie ?\nLes globinopathies causent-elles des douleurs ?\nQuels signes indiquent une surcharge en globines ?\nLes symptômes varient-ils selon le type de globinopathie ?", "url": "https://questionsmedicales.fr/mesh/D005914#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Globines", "description": "Peut-on prévenir les globinopathies ?\nComment réduire le risque de complications ?\nLe dépistage néonatal est-il utile ?\nLes vaccinations sont-elles importantes pour les patients ?\nComment l'éducation peut-elle aider à prévenir les globinopathies ?", "url": "https://questionsmedicales.fr/mesh/D005914#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Globines", "description": "Quels traitements existent pour les globinopathies ?\nLa thérapie génique est-elle efficace pour les globinopathies ?\nComment traiter une anémie causée par des globines ?\nLes médicaments peuvent-ils aider les globinopathies ?\nQuelles sont les options de traitement pour la drépanocytose ?", "url": "https://questionsmedicales.fr/mesh/D005914#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Globines", "description": "Quelles complications peuvent survenir avec les globinopathies ?\nLes globinopathies augmentent-elles le risque d'accidents vasculaires ?\nComment gérer les complications des globinopathies ?\nLes complications peuvent-elles être évitées ?\nLes complications affectent-elles la qualité de vie ?", "url": "https://questionsmedicales.fr/mesh/D005914#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Globines", "description": "Quels sont les facteurs de risque des globinopathies ?\nL'origine ethnique influence-t-elle les globinopathies ?\nLes femmes enceintes doivent-elles être testées ?\nLes antécédents médicaux augmentent-ils le risque ?\nLe mode de vie influence-t-il les globinopathies ?", "url": "https://questionsmedicales.fr/mesh/D005914#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une anomalie des globines ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Des tests sanguins mesurant les niveaux de globines et des électrophorèses sont utilisés." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour les troubles des globines ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests incluent l'électrophorèse des protéines et les tests génétiques." } }, { "@type": "Question", "name": "Quels symptômes indiquent un problème de globines ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Fatigue, pâleur, essoufflement et anomalies sanguines peuvent indiquer un problème." } }, { "@type": "Question", "name": "Les globinopathies sont-elles héréditaires ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines globinopathies comme la drépanocytose sont héréditaires." } }, { "@type": "Question", "name": "Comment évaluer la fonction des globines ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "On évalue la fonction par des tests de saturation en oxygène et des analyses sanguines." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une carence en globines ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent fatigue, faiblesse, et essoufflement lors d'efforts." } }, { "@type": "Question", "name": "Comment reconnaître une globinopathie ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Les signes incluent des douleurs abdominales, des infections fréquentes et une anémie." } }, { "@type": "Question", "name": "Les globinopathies causent-elles des douleurs ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des douleurs peuvent survenir, surtout en cas de crise vaso-occlusive." } }, { "@type": "Question", "name": "Quels signes indiquent une surcharge en globines ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Des signes comme la jaunisse et des douleurs articulaires peuvent apparaître." } }, { "@type": "Question", "name": "Les symptômes varient-ils selon le type de globinopathie ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les symptômes varient selon le type, comme la drépanocytose ou la thalassémie." } }, { "@type": "Question", "name": "Peut-on prévenir les globinopathies ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention est limitée, mais le dépistage génétique peut aider les familles à risque." } }, { "@type": "Question", "name": "Comment réduire le risque de complications ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Un suivi médical régulier et un traitement préventif peuvent réduire les risques." } }, { "@type": "Question", "name": "Le dépistage néonatal est-il utile ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le dépistage néonatal permet de détecter précocement les globinopathies." } }, { "@type": "Question", "name": "Les vaccinations sont-elles importantes pour les patients ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les vaccinations aident à prévenir les infections chez les patients à risque." } }, { "@type": "Question", "name": "Comment l'éducation peut-elle aider à prévenir les globinopathies ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "L'éducation sur les risques et les signes précoces peut aider à une détection rapide." } }, { "@type": "Question", "name": "Quels traitements existent pour les globinopathies ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements incluent transfusions sanguines, médicaments et thérapies géniques." } }, { "@type": "Question", "name": "La thérapie génique est-elle efficace pour les globinopathies ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, la thérapie génique montre des résultats prometteurs pour certaines globinopathies." } }, { "@type": "Question", "name": "Comment traiter une anémie causée par des globines ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement peut inclure des suppléments de fer et des transfusions sanguines." } }, { "@type": "Question", "name": "Les médicaments peuvent-ils aider les globinopathies ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains médicaments aident à gérer les symptômes et à prévenir les complications." } }, { "@type": "Question", "name": "Quelles sont les options de traitement pour la drépanocytose ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Les options incluent des transfusions, des médicaments et des traitements préventifs." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec les globinopathies ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des infections, des crises douloureuses et des problèmes organiques." } }, { "@type": "Question", "name": "Les globinopathies augmentent-elles le risque d'accidents vasculaires ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines globinopathies augmentent le risque d'accidents vasculaires cérébraux." } }, { "@type": "Question", "name": "Comment gérer les complications des globinopathies ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "La gestion inclut un suivi médical, des traitements symptomatiques et des soins préventifs." } }, { "@type": "Question", "name": "Les complications peuvent-elles être évitées ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être évitées par un traitement préventif et un suivi régulier." } }, { "@type": "Question", "name": "Les complications affectent-elles la qualité de vie ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les complications peuvent significativement affecter la qualité de vie des patients." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque des globinopathies ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des antécédents familiaux, l'origine ethnique et certaines conditions médicales." } }, { "@type": "Question", "name": "L'origine ethnique influence-t-elle les globinopathies ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines ethnies, comme les Africains et les Méditerranéens, sont plus à risque." } }, { "@type": "Question", "name": "Les femmes enceintes doivent-elles être testées ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le dépistage des globinopathies est recommandé pour les femmes enceintes à risque." } }, { "@type": "Question", "name": "Les antécédents médicaux augmentent-ils le risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents de maladies sanguines augmentent le risque de globinopathies." } }, { "@type": "Question", "name": "Le mode de vie influence-t-il les globinopathies ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des facteurs comme la nutrition et l'exercice peuvent influencer la santé des globines." } } ] } ] }
Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale

Validation scientifique effectuée le 19/04/2026

Contenu vérifié selon les dernières recommandations médicales

En savoir plus sur Dr Menir

Sous-catégories

27 au total
└─

Cytoglobine

Cytoglobin D000078842 - D12.776.422.316.381
└─

Hémoglobines

Hemoglobins D006454 - D12.776.422.316.762
└─

Myoglobine

Myoglobin D009211 - D12.776.422.316.940
└─└─

Carboxyhémoglobine

Carboxyhemoglobin D002263 - D12.776.422.316.762.149
└─└─

Érythrocruorines

Erythrocruorins D004902 - D12.776.422.316.762.260
└─└─

Hémoglobine foetale

Fetal Hemoglobin D005319 - D12.776.422.316.762.320
└─└─

Hémoglobine A

Hemoglobin A D006441 - D12.776.422.316.762.380
└─└─

Sous-unités de l'hémoglobine

Hemoglobin Subunits D055554 - D12.776.422.316.762.403
└─└─

Hémoglobines anormales

Hemoglobins, Abnormal D006455 - D12.776.422.316.762.426
└─└─

Méthémoglobine

Methemoglobin D008706 - D12.776.422.316.762.571
└─└─

Oxyhémoglobines

Oxyhemoglobins D010108 - D12.776.422.316.762.687
└─└─

Sulfhémoglobine

Sulfhemoglobin D013435 - D12.776.422.316.762.865
└─└─

Hémoglobines tronquées

Truncated Hemoglobins D054793 - D12.776.422.316.762.932
└─└─

Métmyoglobine

Metmyoglobin D008786 - D12.776.422.316.940.500
└─└─└─

Hémoglobine A2

Hemoglobin A2 D006443 - D12.776.422.316.762.380.450
└─└─└─

Globines alpha

alpha-Globins D055542 - D12.776.422.316.762.403.320
└─└─└─

Globines bêta

beta-Globins D055544 - D12.776.422.316.762.403.325
└─└─└─

Hémoglobine C

Hemoglobin C D006444 - D12.776.422.316.762.426.338
└─└─└─

Hémoglobine E

Hemoglobin E D006446 - D12.776.422.316.762.426.375
└─└─└─

Hémoglobine H

Hemoglobin H D006447 - D12.776.422.316.762.426.463
└─└─└─

Hémoglobine J

Hemoglobin J D006448 - D12.776.422.316.762.426.480
└─└─└─

Hémoglobine M

Hemoglobin M D006449 - D12.776.422.316.762.426.510
└─└─└─

Hémoglobine S

Hemoglobin, Sickle D006451 - D12.776.422.316.762.426.588
└─└─└─└─

Globines zêta

zeta-Globins D055543 - D12.776.422.316.762.403.320.500
└─└─└─└─

Globines delta

delta-Globins D055546 - D12.776.422.316.762.403.325.249
└─└─└─└─

Globines epsilon

epsilon-Globins D055547 - D12.776.422.316.762.403.325.374
└─└─└─└─

Globines gamma

gamma-Globins D055545 - D12.776.422.316.762.403.325.500

Auteurs principaux

Mitchell J Weiss

6 publications dans cette catégorie

Affiliations :
  • Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN.
Publications dans "Globines" : Voir toutes les publications (6)

Christophe Lechauve

3 publications dans cette catégorie

Affiliations :
  • Department of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Publications dans "Globines" :

Brant E Isakson

3 publications dans cette catégorie

Affiliations :
  • Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.
  • Department of Molecular Physiology and Biophysics, University of Virginia School of Medicine, Charlottesville, Virginia.
Publications dans "Globines" :

Luc Moens

3 publications dans cette catégorie

Affiliations :
  • Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
Publications dans "Globines" :

Sylvia Dewilde

3 publications dans cette catégorie

Affiliations :
  • Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
Publications dans "Globines" :

Qianqian Zhang

3 publications dans cette catégorie

Affiliations :
  • Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
  • Innovative Research Center for Diagnosis and Therapy of Thalassemias, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Publications dans "Globines" :

Xiangmin Xu

3 publications dans cette catégorie

Affiliations :
  • Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, China.
  • Innovative Research Center for Diagnosis and Therapy of Thalassemias, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Publications dans "Globines" :

Daniela Giordano

3 publications dans cette catégorie

Affiliations :
  • Institute of Biosciences and BioResources (IBBR), CNR, Via Pietro Castellino 111, 80131 Napoli, Italy; Department of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy.
Publications dans "Globines" :

Cinzia Verde

3 publications dans cette catégorie

Affiliations :
  • Institute of Biosciences and BioResources (IBBR), CNR, Via Pietro Castellino 111, 80131 Napoli, Italy; Department of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. Electronic address: c.verde@ibp.cnr.it.
Publications dans "Globines" :

João Pedro Fernandes Queiroz

2 publications dans cette catégorie

Affiliations :
  • Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Brazil. Electronic address: pedroqueiroz@alu.ufc.br.
Publications dans "Globines" :

Bruno Anderson Matias Rocha

2 publications dans cette catégorie

Affiliations :
  • Departamento de Bioquímica e Biologia Molecular, Universidade Federal do Ceará, Brazil. Electronic address: bruno.rocha@ufc.br.
Publications dans "Globines" :

Ruopeng Feng

2 publications dans cette catégorie

Affiliations :
  • Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN.
Publications dans "Globines" :

Peng Huang

2 publications dans cette catégorie

Affiliations :
  • Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA; and.
Publications dans "Globines" :

Lana C Ly

2 publications dans cette catégorie

Affiliations :
  • School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, Australia.
Publications dans "Globines" :

Gerd A Blobel

2 publications dans cette catégorie

Affiliations :
  • Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA; and.
  • Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Publications dans "Globines" :

Kate G R Quinlan

2 publications dans cette catégorie

Affiliations :
  • School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, Australia.
Publications dans "Globines" :

Merlin Crossley

2 publications dans cette catégorie

Affiliations :
  • School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney, NSW, Australia.
Publications dans "Globines" :

Brandon J Reeder

2 publications dans cette catégorie

Affiliations :
  • School of Life Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK.
Publications dans "Globines" :

T C Stevenson Keller

2 publications dans cette catégorie

Affiliations :
  • Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.
  • Department of Molecular Physiology and Biophysics, University of Virginia School of Medicine, Charlottesville, Virginia.
Publications dans "Globines" :

Alexander S Keller

2 publications dans cette catégorie

Affiliations :
  • Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia.
  • Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia.
Publications dans "Globines" :

Sources (81 au total)

Screening for Antibody Deficiencies in Adults by Serum Electrophoresis and Calculated Globin.

11 2023
DOI: 10.1007/s10875-023-01536-1 PMID: 37505322

This study aimed to investigate the correlation between calculated globulin (CG, total protein level minus albumin level) and the gamma globulin fraction (Gamma), obtained from serum protein electroph... Using linear regression models, analyses of CG and Gamma levels correlation with IgG levels in adults were performed. Receiver-operator curves were created to determine cutoff values and the respectiv... A total of 886 samples were analyzed. CG and Gamma were positively and statistically correlated with IgG levels (r... Both CG and Gamma levels determined by protein electrophoresis analysis may be used to screen for antibody deficiencies in adults, enabling earlier diagnosis of antibody deficiencies in a routine clin...

Humans Adult Agammaglobulinemia Electrophoresis Globins +2 autres

α-Globin mutations and Genetic Variants in γ-globin Promoters are Associated with Unelevated Hemoglobin F Expression of Atypical β

18 Jul 2024
DOI: 10.1016/j.arcmed.2024.103055 PMID: 39029212

Excessive expression of hemoglobin F (HbF) is a characteristic feature and important diagnostic marker of β... To investigate determinants contributing to the non-elevation of HbF expression in β... We studied 231 patients with β... Both groups showed similar rates of type β... Cases with HbE predominance with low-HbF levels and undetectable HbA may not be as conclusive as those with homozygous HbE until DNA analysis is performed. Concomitant inheritance of α-thalassemia is ...