questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Hémoprotéines
Globines
Hémoglobines
Hémoglobines anormales
Hémoglobine C
Hémoglobine C : Questions médicales fréquentes
Diagnostic
5
Hémoglobine C
Électrophorèse de l'hémoglobine
Hémoglobine C
Tests de laboratoire
Dépistage néonatal
Hémoglobine C
Symptômes
5
Complications
Hémoglobine C
Prévention
5
Complications
Hémoglobine C
Conseils génétiques
Hémoglobine C
Vaccination
Hémoglobine C
Traitements
5
Transfusion sanguine
Hémoglobine C
Hydroxyurée
Hémoglobine C
Thérapie génique
Hémoglobine C
Analgésiques
Hémoglobine C
Complications
5
Complications
Hémoglobine C
Crise vaso-occlusive
Hémoglobine C
Problèmes hépatiques
Hémoglobine C
Surveillance
Hémoglobine C
Facteurs de risque
5
Facteurs de risque
Hémoglobine C
Origine ethnique
Hémoglobine C
Antécédents familiaux
Hémoglobine C
Mode de vie
Hémoglobine C
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"@type": "Question",
"name": "Les symptômes varient-ils selon l'âge ?",
"position": 9,
"acceptedAnswer": {
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"@type": "Question",
"name": "L'hémoglobine C provoque-t-elle des douleurs ?",
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"@type": "Question",
"name": "Peut-on prévenir l'hémoglobine C ?",
"position": 11,
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}
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{
"@type": "Question",
"name": "Le dépistage est-il recommandé ?",
"position": 12,
"acceptedAnswer": {
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}
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{
"@type": "Question",
"name": "Comment éviter les complications ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne hydratation et des soins médicaux réguliers aident à éviter les complications."
}
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{
"@type": "Question",
"name": "Les conseils génétiques sont-ils utiles ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les conseils génétiques aident les familles à comprendre les risques de transmission."
}
},
{
"@type": "Question",
"name": "Y a-t-il des vaccinations recommandées ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des vaccinations contre certaines infections sont recommandées pour les patients."
}
},
{
"@type": "Question",
"name": "Comment traite-t-on l'hémoglobine C ?",
"position": 16,
"acceptedAnswer": {
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}
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"@type": "Question",
"name": "Les transfusions sont-elles nécessaires ?",
"position": 17,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Y a-t-il des médicaments spécifiques pour l'hémoglobine C ?",
"position": 18,
"acceptedAnswer": {
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"text": "Des médicaments comme l'hydroxyurée peuvent être prescrits pour réduire les crises."
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{
"@type": "Question",
"name": "La thérapie génique est-elle une option ?",
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{
"@type": "Question",
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"position": 20,
"acceptedAnswer": {
"@type": "Answer",
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}
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"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
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},
{
"@type": "Question",
"name": "L'hémoglobine C augmente-t-elle le risque d'infections ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les patients ont un risque accru d'infections en raison de l'anémie et de la splénomégalie."
}
},
{
"@type": "Question",
"name": "Y a-t-il un risque de crise vaso-occlusive ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les crises vaso-occlusives peuvent survenir, provoquant des douleurs intenses."
}
},
{
"@type": "Question",
"name": "Les problèmes hépatiques sont-ils fréquents ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des problèmes hépatiques peuvent survenir, surtout en cas de transfusions fréquentes."
}
},
{
"@type": "Question",
"name": "Comment surveiller les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des examens réguliers et des bilans sanguins aident à surveiller les complications."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de l'hémoglobine C ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des antécédents familiaux et l'origine ethnique, notamment africaine."
}
},
{
"@type": "Question",
"name": "L'origine ethnique influence-t-elle le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes d'origine africaine ou méditerranéenne sont plus à risque."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux sont-ils importants ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, avoir des membres de la famille atteints augmente le risque de développer l'hémoglobine C."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain peut réduire les complications, mais ne prévient pas la condition."
}
},
{
"@type": "Question",
"name": "Les femmes enceintes doivent-elles être testées ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le dépistage est recommandé pour les femmes enceintes à risque d'hémoglobine C."
}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 11/04/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
3Department of Infectious Diseases, Parasitology, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 324, 69120 Heidelberg, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
1Physical Chemistry of Biosystems, Heidelberg University, Im Neuenheimer Feld 253, 69120 Heidelberg, Germany.
7Center for Integrative Medicine and Physics, Institute for Advanced Study, Kyoto University, Kyoto, 606-8501 Japan.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Facility for Functional Peptidomics, Ulm Peptide Pharmaceuticals (U-PEP), Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Core Unit of Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Computational Biochemistry, Center of Medical Biotechnology, University of Duisburg-Essen, 45141, Essen, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Max-Planck-Institute for Polymer Research Mainz, 55128, Mainz, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Central Facility for Electron Microscopy, Ulm University, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hygiene, Ulm University Medical Center, 89081, Ulm, Germany.
Publications dans "Hémoglobine C" :
2 publications dans cette catégorie
Affiliations :
Institute of Molecular Virology, Ulm University Medical Center, 89081, Ulm, Germany. jan.muench@uni-ulm.de.
Core Unit of Mass Spectrometry and Proteomics, Ulm University Medical Center, 89081, Ulm, Germany. jan.muench@uni-ulm.de.
Publications dans "Hémoglobine C" :
The hemoglobin glycation index (HGI) quantifies the mismatch between glycated hemoglobin A1c and average glycemia among individuals. Currently, it is unknown the potential role of HGI in exhaustively ...
A total of 7,345 participants aged at least 40 years and without diabetes were divided into three groups according to the tertile of their baseline HGI level and followed for a median of 3.24 years to...
During follow-up, 742 subjects (263 males and 479 females) developed diabetes mellitus. Higher HGI was associated with an increased risk of diabetes, even when adjusted for confounding factors, and ev...
Participants with a higher HGI were at a higher risk of future diabetes, irrespective of their glycemic conditions. Consequently, HGI may be employed to identify individuals at high risk for diabetes....
The typical rod-shaped HbC crystals in the peripheral blood smear often provide the diagnostic clue to the HbC disease. This case highlights that a careful review of blood film morphology may be helpf...
This study evaluated the effect of continuous glucose monitoring (CGM) versus self-monitored blood glucose (SMGB) in gestational diabetes mellitus (GDM) with hemoglobin A1c (HbA1c) <6%....
From January 2019 to February 2021, 154 GDM patients with HbA1c<6% at 24-28 gestational weeks were recruited and assigned randomly to either SMBG only or CGM in addition to SMBG, with 77 participants ...
Compared with patients in the SMBG group, the CGM group patients had similar times in range (TIRs) after 8 weeks (100.00% (93.75-100.00%) versus 99.14% (90.97-100.00%),...
For GDM patients with HbA1c<6%, regular SMBG is a more economical blood glucose monitoring method and can achieve a similar performance in glycemic control as CGM, while CGM is beneficial for ideal GW...
HbC is a common structural hemoglobinopathy especially in West Africa. Prevalence and regional distribution of HbC in Saudi Arabia are widely undocumented. Patients with homozygous HbC disease may hav...
The current epidemiological study, considered the largest from Saudi Arabia, aimed to evaluate the regional prevalence of the HbC variant among the couples participating in the premarital screening pr...
Data from the PMSGC program were obtained for premarital screening and genetic counseling. The collected data were then entered into the SEHA platform, a centralized electronic repository for the 13 d...
This study included 1,871,184 individuals from 2011 to 2018. Of those, 49.8% were males and 50.2% were females. 112,618 (6.0%) had an abnormal test. Total number of Hb C cases were 778 (0.04%). HbC tr...
HbC is a rare variant in Saudi Arabia with varying regional frequencies. HbC variant is more common in Mecca and Madina regions. The geographic area of HbC distribution differs from the areas with hig...
Antimicrobial peptides (AMPs) are major components of the innate immune defense. Accumulating evidence suggests that the antibacterial activity of many AMPs is dependent on the formation of amyloid-li...
Protective immunity to malaria is mainly antibody-mediated and members of the PfEMP1 family are important targets. Abnormal display of PfEMP1 on the infected erythrocytes (IEs) surface and reduced cyt...
Unstable gamma globin variants can cause transient neonatal hemolytic anemia. We have identified a novel variant in a newborn who presented with jaundice and anemia requiring phototherapy and red bloo...
Maintaining life (respiration), cell death (apoptosis), oxygen transport and immunity are main biological functions of heme containing proteins. These functions are controlled by the axial ligands and...
The aim of this study is to determine the clinical and molecular characteristics enabling differential diagnosis in a group of Turkish children clinically diagnosed with MODY and identify the cut-off ...
The study included 49 patients from 48 unrelated families who were admitted between 2018 and 2020 with a clinical diagnosis of MODY. Clinical and laboratory characteristics of the patients at the time...
A total of 14 (28%) pathogenic/likely pathogenic variants were detected among 49 patients. 11 variants in...
Family history, HbA...
Hb variants prevalent in China are different from those in other countries. We aimed to assess the interference from Hb variants found in China on HbA1c measurement. All Hb variants were confirmed usi...