Two new alkaloids from Portulaca oleracea L. and their bioactivities.
Alkaloids
/ isolation & purification
Antioxidants
/ isolation & purification
Cholinesterase Inhibitors
/ isolation & purification
Indole Alkaloids
Molecular Structure
Phytochemicals
/ isolation & purification
Piperazines
Plant Extracts
/ chemistry
Portulaca
/ chemistry
Spectrometry, Mass, Electrospray Ionization
Anticholinesterase activity
Antioxidant activity
Indole alkaloids
Isolation
Portulaca oleracea L.
Journal
Fitoterapia
ISSN: 1873-6971
Titre abrégé: Fitoterapia
Pays: Netherlands
ID NLM: 16930290R
Informations de publication
Date de publication:
Jul 2019
Jul 2019
Historique:
received:
03
04
2019
revised:
05
05
2019
accepted:
05
05
2019
pubmed:
11
5
2019
medline:
23
8
2019
entrez:
11
5
2019
Statut:
ppublish
Résumé
Two new indole alkaloids, identified as (E)-1-(5,6-dihydroxy-1H-indol-1-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one, named oleraindole A (1), and (E)-1-(5,6-dihydroxy-1H-indol-1-yl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-one, named oleraindole B (2), together with five known indole alkaloids, (-)-neoechinulin A (3), neoechinulin D (4), isoechinulin A (5), MT-6 (6) and echinulin (7) were isolated from the aqueous extract of Portulaca oleracea L. for the first time, using various chromatographic techniques. The structures of seven alkaloids were elucidated by the 1D and 2D NMR and HR-ESI-TOF-MS spectroscopic methods. Oleraindole A (1) and oleraindole B (2) exhibited a relatively high anticholinesterase activity with IC
Identifiants
pubmed: 31075485
pii: S0367-326X(19)30739-7
doi: 10.1016/j.fitote.2019.05.005
pii:
doi:
Substances chimiques
Alkaloids
0
Antioxidants
0
Cholinesterase Inhibitors
0
Indole Alkaloids
0
Phytochemicals
0
Piperazines
0
Plant Extracts
0
neoechinulin A
0
Types de publication
Journal Article
Langues
eng
Pagination
104166Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.