Clinical practice guidelines for the management of olfactory dysfunction - Secondary publication.
Adrenal Cortex Hormones
/ therapeutic use
Chronic Disease
Histamine Antagonists
/ therapeutic use
Humans
Japan
Neurodegenerative Diseases
/ complications
Olfaction Disorders
/ diagnosis
Otolaryngology
Otorhinolaryngologic Surgical Procedures
Prognosis
Rhinitis
/ complications
Sensory Thresholds
Sinusitis
/ complications
Societies, Medical
Clinical practice guideline
Corticosteroids
Neurodegenerative disorders
Olfactory dysfunction
Olfactory training
Treatment
Journal
Auris, nasus, larynx
ISSN: 1879-1476
Titre abrégé: Auris Nasus Larynx
Pays: Netherlands
ID NLM: 7708170
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
04
02
2019
revised:
21
03
2019
accepted:
03
04
2019
pubmed:
12
5
2019
medline:
29
1
2020
entrez:
12
5
2019
Statut:
ppublish
Résumé
To provide an evidence-based recommendation for the management of olfactory dysfunction in accordance with the consensus reached by the Subcommittee of the Japanese Clinical Practice Guideline for olfactory dysfunction in the Japanese Rhinologic Society. Seven clinical questions (CQs) regarding the management of olfactory dysfunction were formulated by the subcommittee of the Japanese Clinical Practice Guideline for olfactory dysfunction. We searched the literature published between April 1990 and September 2014 using PubMed, the Cochrane Library, and Ichushi Web databases. The main search terms were "smell disorder," "olfactory dysfunction," "olfactory loss," "olfactory disturbance," "olfactory impairments," "olfaction disorder," "smell disorder," "anosmia," "cacosmia," and "dysosmia." Based on the results of the literature review and the expert opinion of the Subcommittee, 4 levels of recommendation, from A-strongly recommended to D-not recommended, were adopted for the management of olfactory dysfunction. Both oral and locally administered corticosteroids have been strongly recommended for patients with olfactory dysfunction due to chronic rhinosinusitis. Nasal steroid spray and antihistamine drugs have been moderately recommended for patients with allergic rhinitis. Although no drugs have been deemed to be truly effective for post-viral olfactory dysfunction by randomized-controlled trials (RCTs) or placebo-controlled trials, olfactory training using odorants has been reported to be effective for improving olfactory function. There is considerable evidence that olfactory testing is useful for differential diagnosis, prediction of disease progression, and early detection of cognitive decline in neurodegenerative diseases. The Clinical Practice Guideline has developed recommendations for the management of various aspects of olfactory dysfunction.
Identifiants
pubmed: 31076272
pii: S0385-8146(19)30118-X
doi: 10.1016/j.anl.2019.04.002
pii:
doi:
Substances chimiques
Adrenal Cortex Hormones
0
Histamine Antagonists
0
Types de publication
Journal Article
Practice Guideline
Langues
eng
Sous-ensembles de citation
IM
Pagination
653-662Informations de copyright
Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.