Milk and Dairy Product Consumption and Bladder Cancer Risk: A Systematic Review and Meta-Analysis of Observational Studies.
dairy products
fermented dairy products; whole milk; bladder cancer
meta-analysis; systematic review
milk
Journal
Advances in nutrition (Bethesda, Md.)
ISSN: 2156-5376
Titre abrégé: Adv Nutr
Pays: United States
ID NLM: 101540874
Informations de publication
Date de publication:
01 05 2019
01 05 2019
Historique:
received:
19
07
2018
revised:
04
10
2018
entrez:
16
5
2019
pubmed:
16
5
2019
medline:
21
1
2020
Statut:
ppublish
Résumé
Some studies have reported that milk and dairy product consumption reduces bladder cancer incidence, whereas others have reported null or opposite findings. This meta-analysis of 26 cohort and case-control studies has been conducted to pool the risk of the association between milk and dairy products and bladder cancer. A systematic search in MEDLINE, EMBASE, and the Web of Science (from inception to 30 April 2018) was conducted. Random-effects models were used to compute pooled estimates of RR for high or medium compared with low consumption of milk and dairy. Sensitivity analyses were conducted. Subgroup analyses were performed based on type of dairy, gender, geographic location, and type of study design. Random-effects meta-regression was used to evaluate other confounding factors. Overall, medium compared with low consumption was associated with lower pooled risk of bladder cancer for total dairy products (RR = 0.90; 95% CI: 0.81, 0.98), milk (RR = 0.90; 95% CI: 0.82, 0.98), and fermented dairy products (RR = 0.87; 95% CI: 0.79, 0.96). The inverse association for milk consumption was stronger in Asians (RR = 0.79; 95% CI: 0.59, 0.98) and in cohort design studies (RR = 0.85; 95% CI: 0.71, 0.99). Moreover, high compared with low consumption was significantly associated with a lower pooled risk for milk (RR = 0.89; 95% CI: 0.81, 0.98) and fermented dairy products (RR = 0.78; 95% CI: 0.61, 0.94). However, high compared with low consumption of whole milk was significantly associated with a higher risk (RR = 1.21; 95% CI: 1.04, 1.38). The statistical heterogeneity was considerable. In conclusion, the present meta-analysis suggests a decreased risk of bladder cancer associated with medium consumption of total dairy products and with medium and high consumption of milk and fermented dairy products. An increased risk of bladder cancer was observed with high consumption of whole milk. Interpretations of the results should be made with caution. This review was registered at www.crd.york.ac.uk/prospero as CRD42018097020.
Identifiants
pubmed: 31089737
pii: S2161-8313(22)00211-3
doi: 10.1093/advances/nmy119
pmc: PMC6518155
doi:
Substances chimiques
Dietary Fats
0
Types de publication
Journal Article
Meta-Analysis
Research Support, Non-U.S. Gov't
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
S224-S238Informations de copyright
Copyright © American Society for Nutrition 2019.
Références
J Nutr. 2002 Oct;132(10):2995-8
pubmed: 12368384
Ann Nutr Metab. 2017;70(1):26-33
pubmed: 28125802
Breast Cancer Res Treat. 2010 Jun;121(2):469-77
pubmed: 19851861
BMC Public Health. 2016 Dec 8;16(1):1236
pubmed: 27927192
BJU Int. 2012 Jun;109(11):1594-7
pubmed: 22176770
JAMA. 2000 Apr 19;283(15):2008-12
pubmed: 10789670
Tumour Biol. 2015 Mar;36(3):1567-72
pubmed: 25359617
Eur J Clin Nutr. 2003 Jan;57(1):1-17
pubmed: 12548291
Int J Cancer. 1991 Sep 9;49(2):214-9
pubmed: 1879967
Urol Int. 2002;68(4):273-80
pubmed: 12053032
Stat Med. 2002 Jun 15;21(11):1539-58
pubmed: 12111919
Cancer Causes Control. 2013 May;24(5):885-95
pubmed: 23412804
Urol Int. 1992;49(3):125-9
pubmed: 1466089
Int J Cancer. 2015 Mar 1;136(5):E359-86
pubmed: 25220842
Int J Cancer. 2000 Apr 1;86(1):132-8
pubmed: 10728607
Nutr Cancer. 2011 Nov;63(8):1263-71
pubmed: 22043867
Contemp Clin Trials. 2007 Feb;28(2):105-14
pubmed: 16807131
Urology. 1999 Nov;54(5):823-8
pubmed: 10565741
Int J Mol Sci. 2017 Oct 19;18(10):
pubmed: 29048387
Int J Antimicrob Agents. 2000 Dec;16(4):531-6
pubmed: 11118874
Am J Epidemiol. 2010 Feb 15;171(4):436-46
pubmed: 20042437
Int J Cancer. 2004 Dec 20;112(6):909-19
pubmed: 15316938
Int J Cancer. 2011 Jun 1;128(11):2695-708
pubmed: 20715171
Cancer Causes Control. 2010 Nov;21(11):1745-57
pubmed: 20820901
Am J Clin Nutr. 2015 Jan;101(1):87-117
pubmed: 25527754
Nutr Bull. 2014 Dec;39(4):322-350
pubmed: 25635171
Cancer Causes Control. 2011 Mar;22(3):469-78
pubmed: 21203820
Nutrition. 2016 May;32(5):515-23
pubmed: 26822497
J Epidemiol. 2005 Jun;15 Suppl 2:S190-5
pubmed: 16127233
Nutr Cancer. 2000;38(1):13-22
pubmed: 11341038
Am J Epidemiol. 1979 Sep;110(3):255-63
pubmed: 582494
BMJ. 2007 Jun 30;334(7608):1331-2
pubmed: 17599979
BMJ. 1997 Sep 13;315(7109):629-34
pubmed: 9310563
Br J Cancer. 1990 Mar;61(3):454-9
pubmed: 2328215
Am J Epidemiol. 1988 Jun;127(6):1179-91
pubmed: 3369417
J Natl Cancer Inst. 2004 Jul 7;96(13):1015-22
pubmed: 15240785
Int J Cancer. 2010 Aug 1;127(3):638-45
pubmed: 19957334
Cancer Causes Control. 1996 Jan;7(1):95-100
pubmed: 8850438
J Med Food. 2010 Feb;13(1):13-9
pubmed: 20136431
Nutr Cancer. 1989;12(1):93-101
pubmed: 2710651
Urology. 2010 Feb;75(2):340-6
pubmed: 19819528
Urology. 2011 Dec;78(6):1298-305
pubmed: 22137695
Cell Physiol Biochem. 2015;37(5):1686-92
pubmed: 26545152
Cancer Epidemiol Biomarkers Prev. 1996 Mar;5(3):161-6
pubmed: 8833615
Int J Cancer. 2008 Oct 1;123(7):1649-56
pubmed: 18623082
J Pak Med Assoc. 2013 Feb;63(2):253-7
pubmed: 23894906
Int J Urol. 2004 Jan;11(1):11-9
pubmed: 14678179
Am J Clin Nutr. 2008 Oct;88(4):1083-7
pubmed: 18842797
J Food Drug Anal. 2018 Jul;26(3):927-939
pubmed: 29976412
Neoplasma. 2003;50(3):234-8
pubmed: 12937859
Asian Pac J Cancer Prev. 2014;15(14):5805-9
pubmed: 25081704
Int J Cancer. 1988 Jul 15;42(1):17-22
pubmed: 3391705
Ann Intern Med. 2013 Feb 19;158(4):280-6
pubmed: 23420236
Eur J Epidemiol. 2017 Apr;32(4):269-287
pubmed: 28374228
Nutr Cancer. 1990;13(1-2):89-99
pubmed: 2300498
Food Nutr Res. 2016 Nov 22;60:32527
pubmed: 27882862
Ann Epidemiol. 1993 May;3(3):211-6
pubmed: 8275191
Stat Med. 1999 Oct 30;18(20):2693-708
pubmed: 10521860
Environ Health. 2012 Jun 28;11 Suppl 1:S11
pubmed: 22759493
J Am Coll Nutr. 2000 Apr;19(2 Suppl):119S-136S
pubmed: 10759138
Eur J Cancer Prev. 2001 Oct;10(5):453-8
pubmed: 11711760
J Natl Cancer Inst. 1984 Jun;72(6):1323-5
pubmed: 6587152
N Engl J Med. 1999 May 6;340(18):1390-7
pubmed: 10228189