Survival Rates According to Tumour Location in Patients With Surgically Treated Oral and Oropharyngeal Squamous Cell Carcinoma.
Adult
Aged
Female
Humans
Lymphatic Metastasis
/ pathology
Male
Maxilla
/ pathology
Middle Aged
Mouth Floor
/ pathology
Mouth Neoplasms
/ epidemiology
Neoplasm Staging
Oral Surgical Procedures
Oropharyngeal Neoplasms
/ epidemiology
Palate
/ pathology
Prognosis
Squamous Cell Carcinoma of Head and Neck
/ epidemiology
Survival Rate
Squamous cell carcinoma
oral cancer
oropharyngeal cancer
surgical treatment
survival rates
tumor location
Journal
Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
received:
09
04
2019
revised:
17
04
2019
accepted:
18
04
2019
entrez:
17
5
2019
pubmed:
17
5
2019
medline:
23
5
2019
Statut:
ppublish
Résumé
We evaluated survival rates in surgically-treated oral and oropharyngeal squamous cell carcinoma patients at our clinic, and determined whether survival differed by tumour locations. In a retrospective study, tumour lesions in 1,486 patients were categorized into 6 groups according to tumour location. Patients' age, sex, tumour-node-metastasis classification, resection status, 5-year and disease-specific survival rates were statistically analysed between groups. A significantly inferior disease-specific and lower 5-year survival rates for tumours located at the base of the tongue and oropharynx, and maxilla, due to higher T-stage and incomplete resection status were shown. Cervical lymph node metastasis and distant metastatic spread were more frequently observed with base of the tongue and oropharynx lesions. Attentive inspection and precise clinical examinations of specific oral and oropharyngeal regions are crucial for early diagnosis and treatment. Oral and oropharyngeal tumour locations play important roles in disease prognosis.
Sections du résumé
BACKGROUND/AIM
OBJECTIVE
We evaluated survival rates in surgically-treated oral and oropharyngeal squamous cell carcinoma patients at our clinic, and determined whether survival differed by tumour locations.
PATIENTS AND METHODS
METHODS
In a retrospective study, tumour lesions in 1,486 patients were categorized into 6 groups according to tumour location. Patients' age, sex, tumour-node-metastasis classification, resection status, 5-year and disease-specific survival rates were statistically analysed between groups.
RESULTS
RESULTS
A significantly inferior disease-specific and lower 5-year survival rates for tumours located at the base of the tongue and oropharynx, and maxilla, due to higher T-stage and incomplete resection status were shown. Cervical lymph node metastasis and distant metastatic spread were more frequently observed with base of the tongue and oropharynx lesions.
CONCLUSION
CONCLUSIONS
Attentive inspection and precise clinical examinations of specific oral and oropharyngeal regions are crucial for early diagnosis and treatment. Oral and oropharyngeal tumour locations play important roles in disease prognosis.
Identifiants
pubmed: 31092449
pii: 39/5/2527
doi: 10.21873/anticanres.13374
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2527-2533Informations de copyright
Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.