Effect of Intravenous Dexamethasone on the Regression of Isobaric Bupivacaine Spinal Anesthesia: A Randomized Controlled Trial.
Adult
Aged
Anesthesia, Local
Anesthesia, Spinal
/ methods
Anesthetics, Local
/ administration & dosage
Bupivacaine
/ administration & dosage
Dexamethasone
/ administration & dosage
Double-Blind Method
Female
Humans
Infusions, Intravenous
Injections, Spinal
Male
Middle Aged
Nerve Block
Prospective Studies
Time Factors
Treatment Outcome
Journal
Anesthesia and analgesia
ISSN: 1526-7598
Titre abrégé: Anesth Analg
Pays: United States
ID NLM: 1310650
Informations de publication
Date de publication:
06 2019
06 2019
Historique:
entrez:
17
5
2019
pubmed:
17
5
2019
medline:
23
1
2020
Statut:
ppublish
Résumé
The effect of intravenous dexamethasone on the regression of sensory and motor block after isobaric bupivacaine spinal anesthesia is unknown. We conducted a prospective, double-blind, randomized controlled trial on 60 patients who received intravenously either placebo (group P) or 8-mg dexamethasone (group D) during the intrathecal injection of 12-mg isobaric bupivacaine 0.5%. Primary outcome was the time from bupivacaine injection to regression of 2 dermatomes in relation to the highest dermatome blocked by the spinal local anesthetic. Time to 2-dermatome regression was 85 minutes (74-96 minutes) in group P versus 87 minutes (76-98 minutes) in group D (P = .79).
Identifiants
pubmed: 31094803
doi: 10.1213/ANE.0000000000003670
pii: 00000539-201906000-00041
doi:
Substances chimiques
Anesthetics, Local
0
Dexamethasone
7S5I7G3JQL
Bupivacaine
Y8335394RO
Banques de données
ClinicalTrials.gov
['NCT02627755']
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM