Sero-prevalence of brucellosis among slaughterhouse workers in Bahr el Ghazal region, South Sudan.


Journal

BMC infectious diseases
ISSN: 1471-2334
Titre abrégé: BMC Infect Dis
Pays: England
ID NLM: 100968551

Informations de publication

Date de publication:
22 May 2019
Historique:
received: 22 12 2017
accepted: 03 05 2019
entrez: 23 5 2019
pubmed: 23 5 2019
medline: 23 7 2019
Statut: epublish

Résumé

Brucellosis is an infectious zoonotic disease and is common especially among pastoral communities in most low and middle-income countries. The aim of this study was to determine sero-prevalence, and risk factors of Brucella infection among Slaughterhouse workers, in Bahr el Ghazal region, South Sudan. A cross sectional study was conducted among Slaughterhouse workers in Bahr el Ghazal region, South Sudan from December 2015 to May 2016. A pre-tested questionnaire was used in data collection. Each randomly selected participant was interviewed and a venous blood sample collected. The blood samples were screened for Brucellosis infection using Rose Bengal Plate Test (RBPT) and confirmed using Competitive Enzyme link Immuno Sorbet Assay (c-ELISA). Data was analyzed using Stata version 13 at 95% level of confidence. A total of 234 Slaughterhouse workers were screen for Brucella infection. Overall, a third, 32.1% (75/234) of the participants were sero-positive for brucellosis. The prevalence of brucellosis was higher, 17.1% (40/234) in Wau state compared to other states. There was high prevalence among males, 28.6% (67/234) compared to females 3.4% (8/234). The mean age of study participants was 34.4 ± 9.6 years. A high proportion, 12.8% (30/234) of participants with confirmed brucellosis infection were 31-40 years of age. Brucellosis prevalence was high among butchers, 14.5% (34/234), and meat handlers, 9.0% (21/234). Brucellosis is common among animal slaughterhouse workers in Bahr el Ghazal region, South Sudan. There is need for public awareness campaigns and educational programs to help sensitize communities on Brucella infection.

Sections du résumé

BACKGROUND BACKGROUND
Brucellosis is an infectious zoonotic disease and is common especially among pastoral communities in most low and middle-income countries. The aim of this study was to determine sero-prevalence, and risk factors of Brucella infection among Slaughterhouse workers, in Bahr el Ghazal region, South Sudan.
METHODS METHODS
A cross sectional study was conducted among Slaughterhouse workers in Bahr el Ghazal region, South Sudan from December 2015 to May 2016. A pre-tested questionnaire was used in data collection. Each randomly selected participant was interviewed and a venous blood sample collected. The blood samples were screened for Brucellosis infection using Rose Bengal Plate Test (RBPT) and confirmed using Competitive Enzyme link Immuno Sorbet Assay (c-ELISA). Data was analyzed using Stata version 13 at 95% level of confidence.
RESULTS RESULTS
A total of 234 Slaughterhouse workers were screen for Brucella infection. Overall, a third, 32.1% (75/234) of the participants were sero-positive for brucellosis. The prevalence of brucellosis was higher, 17.1% (40/234) in Wau state compared to other states. There was high prevalence among males, 28.6% (67/234) compared to females 3.4% (8/234). The mean age of study participants was 34.4 ± 9.6 years. A high proportion, 12.8% (30/234) of participants with confirmed brucellosis infection were 31-40 years of age. Brucellosis prevalence was high among butchers, 14.5% (34/234), and meat handlers, 9.0% (21/234).
CONCLUSIONS CONCLUSIONS
Brucellosis is common among animal slaughterhouse workers in Bahr el Ghazal region, South Sudan. There is need for public awareness campaigns and educational programs to help sensitize communities on Brucella infection.

Identifiants

pubmed: 31113372
doi: 10.1186/s12879-019-4066-4
pii: 10.1186/s12879-019-4066-4
pmc: PMC6529993
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

450

Subventions

Organisme : NORHED program at Makerere University for funding the study under the CAPAZOMININTICO project.
ID : CAPAZOMANINTECO Project Number.UGA-13/0031

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Auteurs

Nuol Aywel Madut (NA)

Department of Veterinary Clinical studies, Faculty of Veterinary Science Bahr el Ghazal University, South Sudan, P. O. Box 30, Wau, South Sudan. nmadut@gmail.com.
Department of Biosecurity, Ecosystems &Veterinary Public Health (BEP). College of Vet. Animal Resources & Biosecurity (COVAB), Makerere University, P.O Box 7062, Kampala, Uganda. nmadut@gmail.com.

Moses Ocan (M)

Department of Pharmacology & Therapeutics, College of Health Sciences, Makerere University, P. O. Box, 7062, Kampala, Uganda.

Adrian Muwonge (A)

Department of Genetics and Genomics, The Roslin Institute, University of Edinburgh, Edinburgh, Scotland.

John Bwalya Muma (JB)

Department of Disease Control, School of Veterinary Medicine, University of Zambia, P.O. Box 32379, Lusaka, Zambia.

George William Nasinyama (GW)

Department of Biosecurity, Ecosystems &Veterinary Public Health (BEP). College of Vet. Animal Resources & Biosecurity (COVAB), Makerere University, P.O Box 7062, Kampala, Uganda.

Jacques Godfroid (J)

Department of food Safety and infection Biology, Norwegian School of Veterinary Science, 9010, Troms∅, Norway.

Ambrose Samuel Jubara (AS)

Department of Veterinary Clinical studies, Faculty of Veterinary Science Bahr el Ghazal University, South Sudan, P. O. Box 30, Wau, South Sudan.

Clovice Kankya (C)

Department of Biosecurity, Ecosystems &Veterinary Public Health (BEP). College of Vet. Animal Resources & Biosecurity (COVAB), Makerere University, P.O Box 7062, Kampala, Uganda.

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