Prognostic of Interatrial Block after an Acute ST-Segment Elevation Myocardial Infarction.


Journal

Cardiology
ISSN: 1421-9751
Titre abrégé: Cardiology
Pays: Switzerland
ID NLM: 1266406

Informations de publication

Date de publication:
Historique:
received: 10 12 2018
accepted: 10 03 2019
pubmed: 23 5 2019
medline: 19 12 2019
entrez: 23 5 2019
Statut: ppublish

Résumé

The influence of interatrial block (IAB) in the prognosis after an acute ST-segment elevation myocardial infarction (STEMI) is unknown. To assess the prognostic impact of IAB after an acute STEMI regarding long-term mortality, development of atrial fibrillation, and stroke. Registry of 972 consecutive patients with STEMI and sinus rhythm at discharge, with a long-term follow-up (49.6 ± 24.9 months). P wave duration was analyzed using digital calipers, and patients were divided into three groups: normal P wave duration (<120 ms), partial IAB (pIAB) (P wave ≥120 ms and positive in inferior leads), and advanced IAB (aIAB) (P wave ≥120 ms plus biphasic [positive/negative] morphology in inferior leads). Mean age was 62.6 ± 13.5 years. A total of 708 patients had normal P wave (72.8%), 207 pIAB (21.3%), and 57 aIAB (5.9%). Patients with aIAB were older (mean age 73 years) than the rest (62 years in the other two groups, p < 0.001). They also had a higher rate of hypertension (70 vs. 55% in pIAB and 49% in normal P wave, p = 0.006) and higher all-cause mortality (26.3 vs. 12.6% in pIAB and 10.3% in normal P wave, p = 0.001). However, multivariable analysis did not show an independent association between IAB and prognosis. About a quarter of patients discharged in sinus rhythm after an acute STEMI have IAB. Patients with aIAB have a poor prognosis, although this is explained mainly by the association of aIAB with age and other variables.

Sections du résumé

BACKGROUND BACKGROUND
The influence of interatrial block (IAB) in the prognosis after an acute ST-segment elevation myocardial infarction (STEMI) is unknown.
OBJECTIVES OBJECTIVE
To assess the prognostic impact of IAB after an acute STEMI regarding long-term mortality, development of atrial fibrillation, and stroke.
METHODS METHODS
Registry of 972 consecutive patients with STEMI and sinus rhythm at discharge, with a long-term follow-up (49.6 ± 24.9 months). P wave duration was analyzed using digital calipers, and patients were divided into three groups: normal P wave duration (<120 ms), partial IAB (pIAB) (P wave ≥120 ms and positive in inferior leads), and advanced IAB (aIAB) (P wave ≥120 ms plus biphasic [positive/negative] morphology in inferior leads).
RESULTS RESULTS
Mean age was 62.6 ± 13.5 years. A total of 708 patients had normal P wave (72.8%), 207 pIAB (21.3%), and 57 aIAB (5.9%). Patients with aIAB were older (mean age 73 years) than the rest (62 years in the other two groups, p < 0.001). They also had a higher rate of hypertension (70 vs. 55% in pIAB and 49% in normal P wave, p = 0.006) and higher all-cause mortality (26.3 vs. 12.6% in pIAB and 10.3% in normal P wave, p = 0.001). However, multivariable analysis did not show an independent association between IAB and prognosis.
CONCLUSION CONCLUSIONS
About a quarter of patients discharged in sinus rhythm after an acute STEMI have IAB. Patients with aIAB have a poor prognosis, although this is explained mainly by the association of aIAB with age and other variables.

Identifiants

pubmed: 31117073
pii: 000499501
doi: 10.1159/000499501
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

109-115

Informations de copyright

© 2019 S. Karger AG, Basel.

Auteurs

Vanesa Bruña (V)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.

Jesús Velásquez-Rodríguez (J)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.

María Jesús Valero-Masa (MJ)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.

Beatriz Pérez-Guillem (B)

Universidad Europea Madrid, Madrid, Spain.

Lourdes Vicent (L)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.

Felipe Díez-Delhoyo (F)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.

Carolina Devesa (C)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.

Iago Sousa-Casasnovas (I)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.

Miriam Juárez (M)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.

Antoni Bayés de Luna (A)

Fundació d'Investigació Cardiovascular, ICCC, Hospital de Sant Pau, Barcelona, Spain.

Antoni Bayés-Genís (A)

Hospital Universitari Germans Trias i Pujol, UAB, Badalona, Spain.

Adrian Baranchuk (A)

Queen's University, Kingston, Ontario, Canada.

Francisco Fernández-Avilés (F)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain.
Universidad Complutense Madrid, Madrid, Spain.

Manuel Martínez-Sellés (M)

Department of Cardiology, Hospital General Universitario Gregorio Marañón, CIBERCV, Madrid, Spain, mmselles@secardiologia.es.
Universidad Europea Madrid, Madrid, Spain, mmselles@secardiologia.es.
Universidad Complutense Madrid, Madrid, Spain, mmselles@secardiologia.es.

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