Epstein-Barr Virus Seroprevalence and Primary Infection at the University Hospital Luigi Vanvitelli of Naples from 2007 to 2017.
Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Antibodies, Viral
/ blood
Asymptomatic Infections
/ epidemiology
Child
Child, Preschool
Epstein-Barr Virus Infections
/ diagnosis
Female
Herpesvirus 4, Human
Hospitals, University
Humans
Infant
Infant, Newborn
Italy
/ epidemiology
Male
Middle Aged
Prevalence
Retrospective Studies
Seroepidemiologic Studies
Young Adult
EBV nuclear antigen
Epstein-Barr virus
IgG
IgM
Primary infection
Journal
Intervirology
ISSN: 1423-0100
Titre abrégé: Intervirology
Pays: Switzerland
ID NLM: 0364265
Informations de publication
Date de publication:
2019
2019
Historique:
received:
02
05
2018
accepted:
08
01
2019
pubmed:
23
5
2019
medline:
9
11
2019
entrez:
23
5
2019
Statut:
ppublish
Résumé
Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in "Luigi Vanvitelli" University Hospital in the last 10 years. Our results showed that EBV seroprevalence in our geographical area was 65%. Seroprevalence increased gradually with age with no significant difference between females (49.42%) and males (50.58%). The seropositivity for primary infection was higher in patients about 5 years old, while seropositivity for past infection was predominant in patients of about 35 years old. These results underline that children in our country are still exposed to EBV. The development and the deeper use of an EBV vaccine in the early years of life could represent the solution for this infection.
Identifiants
pubmed: 31117080
pii: 000496828
doi: 10.1159/000496828
doi:
Substances chimiques
Antibodies, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
15-22Informations de copyright
© 2019 S. Karger AG, Basel.