Association of perinatal risk factors with neurological outcome in neonates with hypoxic ischemic encephalopathy.
Hypothermia therapy
hypoxic ischemic encephalopathy
neonate
neurological harm and benefit
perinatal risk factors
Journal
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
ISSN: 1476-4954
Titre abrégé: J Matern Fetal Neonatal Med
Pays: England
ID NLM: 101136916
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
pubmed:
24
5
2019
medline:
22
6
2021
entrez:
24
5
2019
Statut:
ppublish
Résumé
Neonates exposed to perinatal insults typically present with hypoxic ischemic encephalopathy (HIE). The aim of our study was to analyze the association between known risk factors for HIE and the severity of encephalopathy after birth and neurological outcome in neonates during the first 4 d of life. Retrospective cohort study including 174 neonates registered between 2011 and 2013 in the National Asphyxia and Cooling Register of Switzerland. None of the studied perinatal risk factors is associated with the severity of encephalopathy after birth. Fetal distress during labor (OR, 2.06; 95% CI, 1.02-4.25, We identified a constellation of risk factors that influence neurological outcome in neonates with HIE during the first 4 d of life. These findings may help clinicians to counsel parents during the early neonatal period. (ClinicalTrials.gov NCT02800018).
Identifiants
pubmed: 31117854
doi: 10.1080/14767058.2019.1623196
doi:
Banques de données
ClinicalTrials.gov
['NCT02800018']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM