Performance analysis of the transcatheter aortic valve implantation on blood flow hemodynamics: An optical imaging-based in vitro study.


Journal

Artificial organs
ISSN: 1525-1594
Titre abrégé: Artif Organs
Pays: United States
ID NLM: 7802778

Informations de publication

Date de publication:
Oct 2019
Historique:
received: 28 01 2019
revised: 11 04 2019
accepted: 23 05 2019
pubmed: 30 5 2019
medline: 23 2 2020
entrez: 30 5 2019
Statut: ppublish

Résumé

Cardiac implants may have a strong influence on the hemodynamics of the circulatory system. In this study, we aimed at investigating the impact of transcatheter aortic valve implantation (TAVI) devices on blood flow patterns that develop in the ascending aorta under physiological flow conditions in vitro. For this purpose, a noninvasive optical measurement tool, three-dimensional particle tracking velocimetry (3D-PTV), was used in a realistic compliant silicone aortic model. The performance and the influence of two TAVIs and one surgical valve on the aortic flow were investigated. Our results showed that valve design and materials may have a distinct influence on relevant hemodynamic properties, namely kinetic energy, production of turbulence, and shear stresses in the ascending aorta. All properties varied considerably between the different valve models. We found that the total aortic regurgitation composed of the closing volume, transvalvular and paravalvular leakages varied for the three valves investigated. Furthermore, peak mean kinetic energy (MKE) ranged from 61 to 116 J/m

Identifiants

pubmed: 31140632
doi: 10.1111/aor.13504
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

E282-E293

Subventions

Organisme : Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
ID : CR23I3_159686

Informations de copyright

© 2019 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

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Auteurs

Utku Gülan (U)

Institute for Environmental Engineering, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.

Harish Appa (H)

Strait Access Technologies, University of Cape Town, Observatory, South Africa.

Pascal Corso (P)

Institute for Environmental Engineering, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.

Christian Templin (C)

Department of Cardiology, University Heart Center, Zurich, Switzerland.

Deon Bezuidenhout (D)

Strait Access Technologies, University of Cape Town, Observatory, South Africa.
Cardiovascular Research Unit, University of Cape Town, Observatory, South Africa.

Peter Zilla (P)

Strait Access Technologies, University of Cape Town, Observatory, South Africa.
Cardiovascular Research Unit, University of Cape Town, Observatory, South Africa.

Firat Duru (F)

Department of Cardiology, University Heart Center, Zurich, Switzerland.
Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland.

Markus Holzner (M)

Institute for Environmental Engineering, Swiss Federal Institute of Technology Zurich, Zurich, Switzerland.

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