Triplex Hybridization of siRNA with Bifacial Glycopolymer Nucleic Acid Enables Hepatocyte-Targeted Silencing.
Journal
ACS chemical biology
ISSN: 1554-8937
Titre abrégé: ACS Chem Biol
Pays: United States
ID NLM: 101282906
Informations de publication
Date de publication:
21 06 2019
21 06 2019
Historique:
pubmed:
30
5
2019
medline:
15
2
2020
entrez:
30
5
2019
Statut:
ppublish
Résumé
Herein, we describe a versatile non-covalent strategy for packaging nucleic acid cargo with targeting modalities, based on triplex hybridization of oligo-uridylate RNA with bifacial polymer nucleic acid (bP
Identifiants
pubmed: 31141333
doi: 10.1021/acschembio.9b00273
pmc: PMC7001860
mid: NIHMS1069125
doi:
Substances chimiques
Nucleic Acids
0
Polymers
0
RNA, Small Interfering
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
1310-1318Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM111995
Pays : United States
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