[Radiation-induced head and neck pain: Management with botulinum toxin a injections].
Douleurs post-radiques après radiothérapie pour cancer des voies aérodigestives superieures : traitement par injections de toxine botulique A.
Adult
Aged
Botulinum Toxins, Type A
/ therapeutic use
Electromyography
Female
Head and Neck Neoplasms
/ radiotherapy
Humans
Injections, Intramuscular
Male
Middle Aged
Neck Pain
/ drug therapy
Neuromuscular Agents
/ therapeutic use
Radiotherapy
/ adverse effects
Retrospective Studies
Visual Analog Scale
Botulinum toxin
Cancer de la tête et du cou
Douleur
Head neck cancers
Pain
Radiation therapy
Radiothérapie
Toxine botulique
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
ISSN: 1769-6658
Titre abrégé: Cancer Radiother
Pays: France
ID NLM: 9711272
Informations de publication
Date de publication:
Jul 2019
Jul 2019
Historique:
received:
18
09
2018
revised:
05
02
2019
accepted:
07
02
2019
pubmed:
31
5
2019
medline:
2
7
2019
entrez:
1
6
2019
Statut:
ppublish
Résumé
To report the results of Botulinum Toxin A (BTA) for radiation-induced head and neck pain. This single-center retrospective study included all the patients treated at our institution with botulinum toxin A injections for radiation-induced head and neck pain between 2006 and 2017. Pain was evaluated by each patient on a visual analogue scale (VAS) (between 0 and 10) before, and 1 month after the injection. Sixteen patients were included in this series. The mean value of the pain was 8.5 before and 8 after the first injection. The difference was statistically significant (p<0.01). Major response occurred in 15 patients (VAS≤3 after BTA) and complete response in 11 patients (VAS=0 after BTA). Botulinum toxin is an effective treatment for radiation-induced head and neck pain.
Identifiants
pubmed: 31147172
pii: S1278-3218(19)30081-2
doi: 10.1016/j.canrad.2019.02.001
pii:
doi:
Substances chimiques
Neuromuscular Agents
0
Botulinum Toxins, Type A
EC 3.4.24.69
Types de publication
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
312-315Informations de copyright
Copyright © 2019 Société française de radiothérapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.