Biotoxicity of diclofenac on two larval amphibians: Assessment of development, growth, cardiac function and rhythm, behavior and antioxidant system.

Acetylcholinesterase / metabolism Animals Anti-Inflammatory Agents, Non-Steroidal / toxicity Anura / physiology Diclofenac / toxicity Heart / drug effects Larva / drug effects Toxicity Tests Water Pollutants, Chemical / toxicity
Amphibian Diclofenac Ecotoxicology Emerging contaminant

Journal

The Science of the total environment
ISSN: 1879-1026
Titre abrégé: Sci Total Environ
Pays: Netherlands
ID NLM: 0330500

Informations de publication

Date de publication:
15 Sep 2019
Historique:
received: 15 02 2019
revised: 18 05 2019
accepted: 18 05 2019
pubmed: 1 6 2019
medline: 11 7 2019
entrez: 1 6 2019
Statut: ppublish

Résumé

The non-steroidal anti-inflammatory drug diclofenac (DCF) threatens the health of aquatic animals and ecosystems. In the present study, different biological endpoints (mortality, development and growth, abnormalities, cardiotoxicity, neurotoxicity and antioxidant system) were used to characterize the acute and chronic effects of DCF (at concentrations ranging between 125 and 4000 μg L

Identifiants

DOI: 10.1016/j.scitotenv.2019.05.275 PMID: 31150883
pubmed: 31150883
pii: S0048-9697(19)32316-2
doi: 10.1016/j.scitotenv.2019.05.275
pii:
doi:

Substances chimiques

Anti-Inflammatory Agents, Non-Steroidal 0
Water Pollutants, Chemical 0
Diclofenac 144O8QL0L1
Acetylcholinesterase EC 3.1.1.7

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

624-637

Informations de copyright

Copyright © 2019 Elsevier B.V. All rights reserved.

Auteurs

Paola M Peltzer (PM)

Laboratorio de Ecotoxicología, Facultad de Bioquímica y Ciencias Biológicas (FBCB), Universidad Nacional del Litoral (UNL), Santa Fe, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina. Electronic address: paolapeltzer@hotmail.com.

Rafael C Lajmanovich (RC)

Laboratorio de Ecotoxicología, Facultad de Bioquímica y Ciencias Biológicas (FBCB), Universidad Nacional del Litoral (UNL), Santa Fe, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

Candela Martinuzzi (C)

Laboratorio de Ecotoxicología, Facultad de Bioquímica y Ciencias Biológicas (FBCB), Universidad Nacional del Litoral (UNL), Santa Fe, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

Andrés M Attademo (AM)

Laboratorio de Ecotoxicología, Facultad de Bioquímica y Ciencias Biológicas (FBCB), Universidad Nacional del Litoral (UNL), Santa Fe, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

Lucila M Curi (LM)

Laboratorio de Ecotoxicología, Facultad de Bioquímica y Ciencias Biológicas (FBCB), Universidad Nacional del Litoral (UNL), Santa Fe, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.

María T Sandoval (MT)

Catedra de Embriología Animal, Facultad de Ciencias Exactas y Naturales y Agrimensura, Universidad Nacional del Nordeste (UNNE), Corrientes, Argentina.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Carboxylic ester hydrolases › Cholinesterases › Acetylcholinesterase › Biotoxicity of diclofenac on two larval...
questionsmedicales.fr › Eucaryotes › Animaux › Biotoxicity of diclofenac on two larval...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Antirhumatismaux › Anti-inflammatoires non stéroïdiens › Biotoxicity of diclofenac on two larval...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Amphibiens › Anura › Biotoxicity of diclofenac on two larval...
questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides carbocycliques › Phénylacétates › Diclofenac › Biotoxicity of diclofenac on two larval...
questionsmedicales.fr › Système cardiovasculaire › Coeur › Biotoxicity of diclofenac on two larval...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Morphogenèse › Métamorphose biologique › Étapes du cycle de vie › Larve › Biotoxicity of diclofenac on two larval...
questionsmedicales.fr › Techniques d'investigation › Tests de toxicité › Biotoxicity of diclofenac on two larval...
questionsmedicales.fr › Actions chimiques et utilisations › Actions toxiques › Polluants environnementaux › Polluants de l'eau › Polluants chimiques de l'eau › Biotoxicity of diclofenac on two larval...