Ultra-high-performance liquid chromatography coupled to quadrupole orbitrap high-resolution mass spectrometry for multi-residue screening of pesticides, (veterinary) drugs and mycotoxins in edible insects.


Journal

Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639

Informations de publication

Date de publication:
30 Sep 2019
Historique:
received: 03 10 2018
revised: 23 04 2019
accepted: 23 04 2019
entrez: 2 6 2019
pubmed: 4 6 2019
medline: 31 7 2019
Statut: ppublish

Résumé

A generic extraction and UHPLC-Q-Orbitrap™-HRMS method was developed for four insect species (mealworm, grasshopper, house cricket and black soldier fly) analyzing a large spectrum of organic chemical contaminants, including pesticides (n = 25), (veterinary) drugs (n = 29), and mycotoxins (n = 23). To prove the method as 'fit-for-purpose', a successful validation was performed, both qualitatively, by determining the screening detection limit (SDL), selectivity and specificity, as well as semi-quantitatively, by assessing the within-day precision (relative standard deviation (RSD)) and recovery. For both the mealworm, grasshopper, house cricket and black soldier fly, 64, 61, 59 and 62 compounds were detected at the respective SDL levels (1-100 μg kg

Identifiants

pubmed: 31151600
pii: S0308-8146(19)30745-9
doi: 10.1016/j.foodchem.2019.04.082
pii:
doi:

Substances chimiques

Mycotoxins 0
Pesticides 0
Veterinary Drugs 0

Types de publication

Journal Article

Langues

eng

Pagination

187-196

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Ellen De Paepe (E)

Laboratory of Chemical Analysis, Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. Electronic address: ellen.depaepe@ugent.be.

Jella Wauters (J)

Laboratory of Chemical Analysis, Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. Electronic address: jella.wauters@ugent.be.

Mik Van Der Borght (M)

Department of Microbial and Molecular Systems (M(2)S), Lab4food, Faculty of Engineering Technology, KU Leuven, Kleinhoefstraat 4, 2240 Geel, Belgium. Electronic address: mik.vanderborght@kuleuven.be.

Johan Claes (J)

Department of Microbial and Molecular Systems (M(2)S), Lab4food, Faculty of Engineering Technology, KU Leuven, Kleinhoefstraat 4, 2240 Geel, Belgium. Electronic address: johan.claes@kuleuven.be.

Steve Huysman (S)

Laboratory of Chemical Analysis, Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. Electronic address: steve.huysman@ugent.be.

Siska Croubels (S)

Laboratory of Pharmacology and Toxicology, Department of Pharmacology, Toxicology and Biochemistry, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. Electronic address: siska.croubels@ugent.be.

Lynn Vanhaecke (L)

Laboratory of Chemical Analysis, Department of Veterinary Public Health and Food Safety, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium; Institute for Global Food Security, School of Biological Sciences, Queen's University, Belfast, Northern Ireland, United Kingdom. Electronic address: lynn.vanhaecke@ugent.be.

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Classifications MeSH