Preoperative course of patients undergoing endoscopic nasobiliary drainage during the management of resectable perihilar cholangiocarcinoma.
Adult
Aged
Bile Duct Neoplasms
/ diagnosis
Cohort Studies
Databases, Factual
Disease-Free Survival
Drainage
/ methods
Endoscopy
/ methods
Female
Hepatectomy
/ methods
Hospital Mortality
Humans
Japan
Klatskin Tumor
/ diagnosis
Male
Middle Aged
Nasal Cavity
Neoplasm Invasiveness
/ pathology
Neoplasm Staging
Preoperative Care
/ methods
Prognosis
Retrospective Studies
Risk Assessment
Survival Analysis
Treatment Outcome
Waiting Lists
/ mortality
Bile duct
Endoscopic retrograde cholangiopancreatography
Perihilar cholangiocarcinoma
Journal
Journal of hepato-biliary-pancreatic sciences
ISSN: 1868-6982
Titre abrégé: J Hepatobiliary Pancreat Sci
Pays: Japan
ID NLM: 101528587
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
pubmed:
4
6
2019
medline:
29
1
2020
entrez:
4
6
2019
Statut:
ppublish
Résumé
Although there are many studies on technical outcomes of endoscopic nasobiliary drainage (ENBD), no authors reported on preoperative course of patients undergoing ENBD. The aim of this study was to investigate the course of patients with ENBD during the waiting period. Patients who underwent resection of perihilar cholangiocarcinoma (PHCC) between January 2013 and September 2017 were retrospectively reviewed. During the study period, 191 consecutive patients underwent surgical resection of PHCC after ENBD. Of the study patients, 154 (80.6%) patients were discharged, returned to their home, then re-admitted for surgery. The remaining 37 patients were continuously hospitalized. The number of cholangitis events during the waiting period was 0 in 120 patients, 1 in 59 patients, 2 ≤ in 12 patients. Endoscopic re-intervention was needed in 52 patients. The median length between the first admission and surgery was 37 days (range 12-197 days) in the entire cohort; it was longer in patients with portal vein embolization than in those without (43 vs. 27 days, P < 0.001). In patients undergoing resection of PHCC, ENBD is widely tolerable with relatively low incidence of cholangitis and thus recommended for preoperative biliary drainage.
Sections du résumé
BACKGROUND
BACKGROUND
Although there are many studies on technical outcomes of endoscopic nasobiliary drainage (ENBD), no authors reported on preoperative course of patients undergoing ENBD. The aim of this study was to investigate the course of patients with ENBD during the waiting period.
METHODS
METHODS
Patients who underwent resection of perihilar cholangiocarcinoma (PHCC) between January 2013 and September 2017 were retrospectively reviewed.
RESULTS
RESULTS
During the study period, 191 consecutive patients underwent surgical resection of PHCC after ENBD. Of the study patients, 154 (80.6%) patients were discharged, returned to their home, then re-admitted for surgery. The remaining 37 patients were continuously hospitalized. The number of cholangitis events during the waiting period was 0 in 120 patients, 1 in 59 patients, 2 ≤ in 12 patients. Endoscopic re-intervention was needed in 52 patients. The median length between the first admission and surgery was 37 days (range 12-197 days) in the entire cohort; it was longer in patients with portal vein embolization than in those without (43 vs. 27 days, P < 0.001).
CONCLUSIONS
CONCLUSIONS
In patients undergoing resection of PHCC, ENBD is widely tolerable with relatively low incidence of cholangitis and thus recommended for preoperative biliary drainage.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
341-347Informations de copyright
© 2019 Japanese Society of Hepato-Biliary-Pancreatic Surgery.