Consistency checks to improve measurement with the Montgomery-Asberg Depression Rating Scale (MADRS).


Journal

Journal of affective disorders
ISSN: 1573-2517
Titre abrégé: J Affect Disord
Pays: Netherlands
ID NLM: 7906073

Informations de publication

Date de publication:
01 09 2019
Historique:
received: 20 12 2018
revised: 27 03 2019
accepted: 31 05 2019
pubmed: 9 6 2019
medline: 4 6 2020
entrez: 9 6 2019
Statut: ppublish

Résumé

International Society for CNS Clinical Trials and Methodology convened an expert Working Group that assembled consistency/inconsistency flags for the Montgomery-Asberg Depression Rating Scale (MADRS). Twenty-two flags were identified. Seven flags are believed to be strong flags that suggest that a thorough review of rating is warranted. The flags were applied to assessments derived from the NEWMEDS data repository. Almost 65% of ratings had at least one inconsistency flag raised and 22% had two or more. Application of flags to clinical ratings may improve reliability of ratings and validity of trials.

Identifiants

pubmed: 31176186
pii: S0165-0327(18)33210-5
doi: 10.1016/j.jad.2019.05.077
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

143-147

Informations de copyright

Copyright © 2019. Published by Elsevier B.V.

Auteurs

Jonathan Rabinowitz (J)

Bar Ilan University, Ramat Gan, Israel. Electronic address: jonathan.rabinowitz@biu.ac.il.

Nina R Schooler (NR)

SUNY Downstate Medical Center, 450 Clarkson Avenue, MSC 1203, Brooklyn, NY 11203, United States.

Brianne Brown (B)

Janssen Scientific Affairs, LLC, 1125 Trenton-Harbourton Rd, Titusville, NJ 08560, United States.

Mads Dalsgaard (M)

Lundbeck A/S, Ottiliavej 9, Valby 2500, Denmark.

Nina Engelhardt (N)

Intra-Cellular Therapies, 430 East 29th Street, Suite 900, New York, NY 10016, United States.

Gretchen Friedberger (G)

Bracket Global, LLC, PO Box 7137, McLean, VA 22106, United States.

Bruce J Kinon (BJ)

Lundbeck North America, 6 Parkway North, Suite 400, Deerfield, IL 60015, United States.

Daniel Lee (D)

Food and Drug Administration, Division of Psychiatry Products, 10903 New Hampshire Ave, Silver Spring, MD 20993-0002, United States.

Felice Ockun (F)

Medavante-ProPhase LLC, 3 Park Avenue, New York, NY 10016, United States.

Atul Mahableshwarkar (A)

BlackThorn Therapeutics Inc., 780 Brannan St, San Francisco, CA, United States.

Joyce Tsai (J)

Sunovion Pharmaceuticals, One Bridge Plaza North, Suite 510, Fort Lee, NJ 07024, United States.

Janet B W Williams (JBW)

Columbia University Department of Psychiatry c/o 2466 Westlake Ave N., #19, Seattle, WA 98109, United States.

Colin Sauder (C)

Adams Clinical, 521 Mt Auburn St, Suite 107, Watertown, MA 02472, United States; UT Health San Antonio, Department of Psychiatry, 7703 Floyd Curl Drive, San Antonio TX 78229, United States.

Christian Yavorsky (C)

Cronos CCS, 201 South Main Street, Lambertville, NJ 08530, United States.

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Classifications MeSH